The cellular expression and proteolytic processing of the amyloid precursor protein is independent of TDP-43

Alzheimer’s disease (AD) is a neurodegenerative condition, of which one of the cardinal pathological hallmarks is the extracellular accumulation of amyloid β (Aβ) peptides. These peptides are generated via proteolysis of the amyloid precursor protein (APP), in a manner dependent on the β-secretase,...

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Detalles Bibliográficos
Autores principales: Hicks, David A., Jones, Alys C., Pickering-Brown, Stuart M., Hooper, Nigel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Molecular Bases of Health & Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7189496/
https://www.ncbi.nlm.nih.gov/pubmed/32301481
http://dx.doi.org/10.1042/BSR20200435

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7189496/
https://www.ncbi.nlm.nih.gov/pubmed/32301481
http://dx.doi.org/10.1042/BSR20200435

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