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C9orf72 associates with inactive Rag GTPases and regulates mTORC1‐mediated autophagosomal and lysosomal biogenesis

GGGGCC repeat expansion in C9orf72 is the most common genetic cause in both frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS), two neurodegenerative disorders in association with aging. Bidirectional repeat expansions in the noncoding region of C9orf72 have been shown to produce...

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Detalles Bibliográficos
Autores principales:	Wang, Mingmei, Wang, Hongfeng, Tao, Zhouteng, Xia, Qin, Hao, Zongbing, Prehn, Jochen H. M., Zhen, Xuechu, Wang, Guanghui, Ying, Zheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7189992/ https://www.ncbi.nlm.nih.gov/pubmed/32100453 http://dx.doi.org/10.1111/acel.13126

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