Lymphocyte Subsets in HIV-Exposed Uninfected Infants: The Impact of Neonatal Postexposure Prophylaxis With Zidovudine

HIV-exposed, uninfected (HEU) infants receiving neonatal postexposure prophylaxis with zidovudine showed nonsignificant trends of lower CD4 and CD8 T cells as well as CD19 B cells than those who did not, suggesting toxicity that might impact the overall health of HEU children.

Detalles Bibliográficos
Autores principales: Greiter, Beat M, Kahlert, Christian R, Eberhard, Nadia, Sultan-Beyer, Leila, Berger, Christoph, Paioni, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190205/
https://www.ncbi.nlm.nih.gov/pubmed/32368562
http://dx.doi.org/10.1093/ofid/ofaa108
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author Greiter, Beat M
Kahlert, Christian R
Eberhard, Nadia
Sultan-Beyer, Leila
Berger, Christoph
Paioni, Paolo
author_facet Greiter, Beat M
Kahlert, Christian R
Eberhard, Nadia
Sultan-Beyer, Leila
Berger, Christoph
Paioni, Paolo
author_sort Greiter, Beat M
collection PubMed
description HIV-exposed, uninfected (HEU) infants receiving neonatal postexposure prophylaxis with zidovudine showed nonsignificant trends of lower CD4 and CD8 T cells as well as CD19 B cells than those who did not, suggesting toxicity that might impact the overall health of HEU children.
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spelling pubmed-71902052020-05-04 Lymphocyte Subsets in HIV-Exposed Uninfected Infants: The Impact of Neonatal Postexposure Prophylaxis With Zidovudine Greiter, Beat M Kahlert, Christian R Eberhard, Nadia Sultan-Beyer, Leila Berger, Christoph Paioni, Paolo Open Forum Infect Dis Brief Report HIV-exposed, uninfected (HEU) infants receiving neonatal postexposure prophylaxis with zidovudine showed nonsignificant trends of lower CD4 and CD8 T cells as well as CD19 B cells than those who did not, suggesting toxicity that might impact the overall health of HEU children. Oxford University Press 2020-03-28 /pmc/articles/PMC7190205/ /pubmed/32368562 http://dx.doi.org/10.1093/ofid/ofaa108 Text en © The Author(s) 2020. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Report
Greiter, Beat M
Kahlert, Christian R
Eberhard, Nadia
Sultan-Beyer, Leila
Berger, Christoph
Paioni, Paolo
Lymphocyte Subsets in HIV-Exposed Uninfected Infants: The Impact of Neonatal Postexposure Prophylaxis With Zidovudine
title Lymphocyte Subsets in HIV-Exposed Uninfected Infants: The Impact of Neonatal Postexposure Prophylaxis With Zidovudine
title_full Lymphocyte Subsets in HIV-Exposed Uninfected Infants: The Impact of Neonatal Postexposure Prophylaxis With Zidovudine
title_fullStr Lymphocyte Subsets in HIV-Exposed Uninfected Infants: The Impact of Neonatal Postexposure Prophylaxis With Zidovudine
title_full_unstemmed Lymphocyte Subsets in HIV-Exposed Uninfected Infants: The Impact of Neonatal Postexposure Prophylaxis With Zidovudine
title_short Lymphocyte Subsets in HIV-Exposed Uninfected Infants: The Impact of Neonatal Postexposure Prophylaxis With Zidovudine
title_sort lymphocyte subsets in hiv-exposed uninfected infants: the impact of neonatal postexposure prophylaxis with zidovudine
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190205/
https://www.ncbi.nlm.nih.gov/pubmed/32368562
http://dx.doi.org/10.1093/ofid/ofaa108
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