Cargando…

A complex IRES at the 5'-UTR of a viral mRNA assembles a functional 48S complex via an uAUG intermediate

Taking control of the cellular apparatus for protein production is a requirement for virus progression. To ensure this control, diverse strategies of cellular mimicry and/or ribosome hijacking have evolved. The initiation stage of translation is especially targeted as it involves multiple steps and...

Descripción completa

Detalles Bibliográficos
Autores principales: Neupane, Ritam, Pisareva, Vera P, Rodriguez, Carlos F, Pisarev, Andrey V, Fernández, Israel S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190351/
https://www.ncbi.nlm.nih.gov/pubmed/32286223
http://dx.doi.org/10.7554/eLife.54575