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Loss of Doc2b does not influence transmission at Purkinje cell to deep nuclei synapses under physiological conditions

Doc2a and Doc2b are high-affinity calcium-binding proteins that interact with SNARE proteins and phospholipids. Experiments performed on cultured cells indicated that Doc2 proteins promote spontaneous vesicle fusion and asynchronous neurotransmitter release, regulate vesicle priming, mediate augment...

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Detalles Bibliográficos
Autores principales: Khan, Mehak M, Regehr, Wade G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190354/
https://www.ncbi.nlm.nih.gov/pubmed/32347796
http://dx.doi.org/10.7554/eLife.55165