CDK13 cooperates with CDK12 to control global RNA polymerase II processivity

The RNA polymerase II (POLII)–driven transcription cycle is tightly regulated at distinct checkpoints by cyclin-dependent kinases (CDKs) and their cognate cyclins. The molecular events underpinning transcriptional elongation, processivity, and the CDK-cyclin pair(s) involved remain poorly understood...

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Detalles Bibliográficos
Autores principales: Fan, Zheng, Devlin, Jennifer R., Hogg, Simon J., Doyle, Maria A., Harrison, Paul F., Todorovski, Izabela, Cluse, Leonie A., Knight, Deborah A., Sandow, Jarrod J., Gregory, Gareth, Fox, Andrew, Beilharz, Traude H., Kwiatkowski, Nicholas, Scott, Nichollas E., Vidakovic, Ana Tufegdzic, Kelly, Gavin P., Svejstrup, Jesper Q., Geyer, Matthias, Gray, Nathanael S., Vervoort, Stephin J., Johnstone, Ricky W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190357/
https://www.ncbi.nlm.nih.gov/pubmed/32917631
http://dx.doi.org/10.1126/sciadv.aaz5041

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