Cargando…

Immunohistochemical Evaluation and Clinicopathological Correlation of Mer and Axl Tyrosine Kinase TAM Receptors in Cutaneous Melanoma

BACKGROUND: Malignant melanoma (MM) is potentially the most dangerous form of skin tumor. In the last few years, the so-called TAM receptors, a unique family of tyrosine kinase (TK) receptors, have become increasingly important. OBJECTIVES: To evaluate Mer and Axl TAM receptor expression to find cli...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pontara, Andrea, Paolino, Giovanni, Gregorc, Vanesa, Mercuri, Santo Raffaele, Bulotta, Alessandra, Bearzi, Pietro, Doglioni, Claudio, Rizzo, Nathalie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Derm101.com 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190557/ https://www.ncbi.nlm.nih.gov/pubmed/32363092 http://dx.doi.org/10.5826/dpc.1002a29

Ejemplares similares

Spontaneous Regression of Primary Melanoma and Multiple Melanocytic Nevi in a Patient With Metastatic Melanoma
por: Paolino, Giovanni, et al.
Publicado: (2020)

The TAM receptor tyrosine kinases Axl and Mer drive the maintenance of highly phagocytic macrophages
por: Jiménez-García, Lidia, et al.
Publicado: (2022)

Differential regulation of hepatic physiology and injury by the TAM receptors Axl and Mer
por: Zagórska, Anna, et al.
Publicado: (2020)

Targeting Tyro3, Axl and MerTK (TAM receptors): implications for macrophages in the tumor microenvironment
por: Myers, Kayla V., et al.
Publicado: (2019)

Onset of vitiligo in a patient with acquired secondary hypogonadism under treatment with testosterone gel 2%: inside the pathogenesis()()
por: Paolino, Giovanni, et al.
Publicado: (2020)

Dual targeting of TAM receptors Tyro3, Axl, and MerTK: Role in tumors and the tumor immune microenvironment
por: Wang, Kai-Hung, et al.
Publicado: (2020)

Regulation of brain endothelial cell physiology by the TAM receptor tyrosine kinase Mer
por: Happonen, Kaisa E., et al.
Publicado: (2023)

Normalization of TAM post-receptor signaling reveals a cell invasive signature for Axl tyrosine kinase
por: Kimani, Stanley G., et al.
Publicado: (2016)

Clinicopathological and Dermoscopic Baselines in Patients with Lynch Syndrome
por: Paolino, Giovanni, et al.
Publicado: (2022)

Key Roles of AXL and MER Receptor Tyrosine Kinases in Resistance to Multiple Anticancer Therapies
por: Schoumacher, Marie, et al.
Publicado: (2017)

Structure-activity relationship of 7-aryl-2-anilino-pyrrolopyrimidines as Mer and Axl tyrosine kinase inhibitors
por: Chung, Shin Hyuck, et al.
Publicado: (2020)

Axl and MerTK receptor tyrosine kinases maintain human macrophage efferocytic capacity in the presence of viral triggers
por: Grabiec, Aleksander M, et al.
Publicado: (2018)

Overexpression of the Axl tyrosine kinase receptor in cutaneous SCC-derived cell lines and tumours
por: Green, J, et al.
Publicado: (2006)

Roles of Sialic Acid, AXL, and MER Receptor Tyrosine Kinases in Mumps Virus Infection of Mouse Sertoli and Leydig Cells
por: Wang, Fei, et al.
Publicado: (2020)

Tyrosine Kinase Receptors Axl and MerTK Mediate the Beneficial Effect of Electroacupuncture in a Cuprizone-Induced Demyelinating Model
por: Zou, Zaofeng, et al.
Publicado: (2020)

Preclinical Characterization of XL092, a Novel Receptor Tyrosine Kinase Inhibitor of MET, VEGFR2, AXL, and MER
por: Hsu, Jeff, et al.
Publicado: (2023)

Cutaneous pseudolymphoma: A clinicopathological study and immunohistochemical patterns
por: Sari Aslani, Fatemeh, et al.
Publicado: (2021)

Loss of the TAM Receptor Axl Ameliorates Severe Zika Virus Pathogenesis and Reduces Apoptosis in Microglia
por: Hastings, Andrew K., et al.
Publicado: (2019)

TAM receptors Tyro3 and Mer as novel targets in colorectal cancer
por: Schmitz, Robin, et al.
Publicado: (2016)

Perineural Invasion and TAMs in Pancreatic Ductal Adenocarcinomas: Review of the Original Pathology Reports Using Immunohistochemical Enhancement and Relationships with Clinicopathological Features
por: Zeng, Linjuan, et al.
Publicado: (2014)

A Functional Role of GAS6/TAM in Nonalcoholic Steatohepatitis Progression Implicates AXL as Therapeutic Target
por: Tutusaus, Anna, et al.
Publicado: (2019)

Morphea after SARS-CoV2 vaccine()
por: Paolino, Giovanni, et al.
Publicado: (2023)

The Receptor Tyrosine Kinase AXL in Cancer Progression
por: Rankin, Erinn B., et al.
Publicado: (2016)

Coordinated expression of tyro3, axl, and mer receptors in macrophage ontogeny
por: Malawista, Anna, et al.
Publicado: (2016)

Development of a Spontaneous Liver Disease Resembling Autoimmune Hepatitis in Mice Lacking Tyro3, Axl and Mer Receptor Tyrosine Kinases
por: Qi, Nan, et al.
Publicado: (2013)

Cutaneous Carcinosarcoma: a Clinicopathologic and Immunohistochemical Analysis of 11 Korean Cases
por: Kwak, Hyun-Bin, et al.
Publicado: (2018)

The Significance of Tumor Budding and Immunohistochemical Axl Expression in Gallbladder Adenocarcinomas
por: Öz, Özden, et al.
Publicado: (2022)

Mer or Axl Receptor Tyrosine Kinase Inhibition Promotes Apoptosis, Blocks Growth, and Enhances Chemosensitivity of Human Non-Small Cell Lung Cancer
por: Linger, Rachel M.A., et al.
Publicado: (2012)

Case report: EML4::NTRK3 gene fusion in a patient with metastatic lung adenocarcinoma successfully treated with entrectinib
por: Lazzari, Chiara, et al.
Publicado: (2022)

Case Report of Dermoscopic Aspects and Reflectance Confocal Microscopy Description of Segmental Leiomyoma and Relative Management
por: Paolino, Giovanni, et al.
Publicado: (2022)

New Insights into the Role of Tyro3, Axl, and Mer Receptors in Rheumatoid Arthritis
por: Pagani, Sara, et al.
Publicado: (2020)

Quantitative Tyrosine Phosphoproteome Profiling of AXL Receptor Tyrosine Kinase Signaling Network
por: Wu, Xinyan, et al.
Publicado: (2021)

The Role of TAM Family Receptors in Immune Cell Function: Implications for Cancer Therapy
por: Paolino, Magdalena, et al.
Publicado: (2016)

AXL receptor tyrosine kinase as a therapeutic target in NSCLC
por: Okimoto, Ross A, et al.
Publicado: (2015)

Implications of the Receptor Tyrosine Kinase Axl in Gastric Cancer Progression
por: He, Lirui, et al.
Publicado: (2020)

Axl receptor tyrosine kinase is a regulator of apolipoprotein E
por: Zhao, Wenchen, et al.
Publicado: (2020)

Predicting the Specificity- Determining Positions of Receptor Tyrosine Kinase Axl
por: Karakulak, Tülay, et al.
Publicado: (2021)

Anifrolumab for Moderate and Severe Muco-Cutaneous Lupus Erythematosus: A Monocentric Experience and Review of the Current Literature
por: Paolino, Giovanni, et al.
Publicado: (2023)

Implication of the Receptor Tyrosine Kinase AXL in Head and Neck Cancer Progression
por: von Mässenhausen, Anne, et al.
Publicado: (2016)

AXL receptor tyrosine kinase is required for T cell priming and antiviral immunity
por: Schmid, Edward T, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_u3kaie48u3u2jgsa4fvmjr03u6