Tumor progression and chromatin landscape of lung cancer are regulated by the lineage factor GATA6

Lineage selective transcription factors (TFs) are important regulators of tumorigenesis, but their biological functions are often context dependent with undefined epigenetic mechanisms of action. In this study, we uncover a conditional role for the endodermal and pulmonary specifying TF GATA6 in lun...

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Detalles Bibliográficos
Autores principales: Arnal-Estapé, Anna, Cai, Wesley L., Albert, Alexandra E., Zhao, Minghui, Stevens, Laura E., López-Giráldez, Francesc, Patel, Kiran D., Tyagi, Siddhartha, Schmitt, Earlene M., Westbrook, Thomas F., Nguyen, Don X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190573/
https://www.ncbi.nlm.nih.gov/pubmed/32157212
http://dx.doi.org/10.1038/s41388-020-1246-z

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