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Tet2-mediated epigenetic drive for astrocyte differentiation from embryonic neural stem cells

DNA methylation and demethylation at CpG di-nucleotide sites plays important roles in cell fate specification of neural stem cells (NSCs). We have previously reported that DNA methyltransferases, Dnmt1and Dnmt3a, serve to suppress precocious astrocyte differentiation from NSCs via methylation of ast...

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Detalles Bibliográficos
Autores principales:	He, Fei, Wu, Hao, Zhou, Liqiang, Lin, Quan, Cheng, Yin, Sun, Yi E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190615/ https://www.ncbi.nlm.nih.gov/pubmed/32377393 http://dx.doi.org/10.1038/s41420-020-0264-5

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