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Maternal sleep quality during pregnancy is associated with neonatal auditory ERPs

Poor maternal sleep quality during pregnancy may act as a prenatal stress factor for the fetus and associate with neonate neurocognition, for example via fetal programming. The impacts of worsened maternal sleep on neonatal development and, more specifically on neonatal auditory brain responses, hav...

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Autores principales: Lavonius, Maria, Railo, Henry, Karlsson, Linnea, Wikström, Valtteri, Tuulari, Jetro J., Scheinin, Noora M., Paavonen, E. Juulia, Polo-Kantola, Päivi, Karlsson, Hasse, Huotilainen, Minna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190640/
https://www.ncbi.nlm.nih.gov/pubmed/32350333
http://dx.doi.org/10.1038/s41598-020-64160-8
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author Lavonius, Maria
Railo, Henry
Karlsson, Linnea
Wikström, Valtteri
Tuulari, Jetro J.
Scheinin, Noora M.
Paavonen, E. Juulia
Polo-Kantola, Päivi
Karlsson, Hasse
Huotilainen, Minna
author_facet Lavonius, Maria
Railo, Henry
Karlsson, Linnea
Wikström, Valtteri
Tuulari, Jetro J.
Scheinin, Noora M.
Paavonen, E. Juulia
Polo-Kantola, Päivi
Karlsson, Hasse
Huotilainen, Minna
author_sort Lavonius, Maria
collection PubMed
description Poor maternal sleep quality during pregnancy may act as a prenatal stress factor for the fetus and associate with neonate neurocognition, for example via fetal programming. The impacts of worsened maternal sleep on neonatal development and, more specifically on neonatal auditory brain responses, have not been studied. A total of 155 mother-neonate dyads drawn from the FinnBrain Birth Cohort Study participated in our study including maternal self-report questionnaires on sleep at gestational week 24 and an event-related potential (ERP) measurement among 1-2-day-old neonates. For sleep quality assessment, the Basic Nordic Sleep Questionnaire (BNSQ) was used and calculated scores for (1) insomnia, (2) subjective sleep loss and (3) sleepiness were formed and applied in the analyses. In the auditory ERP protocol, three emotionally uttered pseudo words (in happy, angry and sad valence) were presented among neutrally uttered pseudo words. To study the relations between prenatal maternal sleep quality and auditory emotion-related ERP responses, mixed-effects regression models were computed for early (100–200 ms) and late (300–500 ms) ERP response time-windows. All of the selected BNSQ scores were associated with neonatal ERP responses for happy and angry emotion stimuli (sleep loss and sleepiness in the early, and insomnia, sleep loss and sleepiness in the late time-window). For sad stimuli, only maternal sleep loss predicted the neonatal ERP response in the late time-window, likely because the overall ERP was weakest in the sad condition. We conclude that maternal sleep quality during pregnancy is associated with changes in neonatal auditory ERP responses.
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spelling pubmed-71906402020-05-05 Maternal sleep quality during pregnancy is associated with neonatal auditory ERPs Lavonius, Maria Railo, Henry Karlsson, Linnea Wikström, Valtteri Tuulari, Jetro J. Scheinin, Noora M. Paavonen, E. Juulia Polo-Kantola, Päivi Karlsson, Hasse Huotilainen, Minna Sci Rep Article Poor maternal sleep quality during pregnancy may act as a prenatal stress factor for the fetus and associate with neonate neurocognition, for example via fetal programming. The impacts of worsened maternal sleep on neonatal development and, more specifically on neonatal auditory brain responses, have not been studied. A total of 155 mother-neonate dyads drawn from the FinnBrain Birth Cohort Study participated in our study including maternal self-report questionnaires on sleep at gestational week 24 and an event-related potential (ERP) measurement among 1-2-day-old neonates. For sleep quality assessment, the Basic Nordic Sleep Questionnaire (BNSQ) was used and calculated scores for (1) insomnia, (2) subjective sleep loss and (3) sleepiness were formed and applied in the analyses. In the auditory ERP protocol, three emotionally uttered pseudo words (in happy, angry and sad valence) were presented among neutrally uttered pseudo words. To study the relations between prenatal maternal sleep quality and auditory emotion-related ERP responses, mixed-effects regression models were computed for early (100–200 ms) and late (300–500 ms) ERP response time-windows. All of the selected BNSQ scores were associated with neonatal ERP responses for happy and angry emotion stimuli (sleep loss and sleepiness in the early, and insomnia, sleep loss and sleepiness in the late time-window). For sad stimuli, only maternal sleep loss predicted the neonatal ERP response in the late time-window, likely because the overall ERP was weakest in the sad condition. We conclude that maternal sleep quality during pregnancy is associated with changes in neonatal auditory ERP responses. Nature Publishing Group UK 2020-04-29 /pmc/articles/PMC7190640/ /pubmed/32350333 http://dx.doi.org/10.1038/s41598-020-64160-8 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Lavonius, Maria
Railo, Henry
Karlsson, Linnea
Wikström, Valtteri
Tuulari, Jetro J.
Scheinin, Noora M.
Paavonen, E. Juulia
Polo-Kantola, Päivi
Karlsson, Hasse
Huotilainen, Minna
Maternal sleep quality during pregnancy is associated with neonatal auditory ERPs
title Maternal sleep quality during pregnancy is associated with neonatal auditory ERPs
title_full Maternal sleep quality during pregnancy is associated with neonatal auditory ERPs
title_fullStr Maternal sleep quality during pregnancy is associated with neonatal auditory ERPs
title_full_unstemmed Maternal sleep quality during pregnancy is associated with neonatal auditory ERPs
title_short Maternal sleep quality during pregnancy is associated with neonatal auditory ERPs
title_sort maternal sleep quality during pregnancy is associated with neonatal auditory erps
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190640/
https://www.ncbi.nlm.nih.gov/pubmed/32350333
http://dx.doi.org/10.1038/s41598-020-64160-8
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