Whole transcriptome analysis and validation of metabolic pathways in subcutaneous adipose tissues during FGF21-induced weight loss in non-human primates

Fibroblast growth factor 21 (FGF21) induces weight loss in mouse, monkey, and human studies. In mice, FGF21 is thought to cause weight loss by stimulating thermogenesis, but whether FGF21 increases energy expenditure (EE) in primates is unclear. Here, we explore the transcriptional response and gene...

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Detalles Bibliográficos
Autores principales: Murray, Sara A., Dalbøge, Louise S., Baquero, Karalee, Sanford, Christina A., Misquith, Ayesha, Mercer, Aaron J., Meek, Thomas H., Guldbrandt, Mette, Andersen, Birgitte, Kievit, Paul, Grove, Kevin L., Kutlu, Burak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190698/
https://www.ncbi.nlm.nih.gov/pubmed/32350364
http://dx.doi.org/10.1038/s41598-020-64170-6

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