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The Effect of Force-Field Parameters on Cytochrome P450-Membrane Interactions: Structure and Dynamics

The simulation of membrane proteins requires compatible protein and lipid force fields that reproduce the properties of both the protein and the lipid bilayer. Cytochrome P450 enzymes are bitopic membrane proteins with a transmembrane helical anchor and a large cytosolic globular domain that dips in...

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Detalles Bibliográficos
Autores principales:	Mustafa, Ghulam, Nandekar, Prajwal P., Mukherjee, Goutam, Bruce, Neil J., Wade, Rebecca C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190701/ https://www.ncbi.nlm.nih.gov/pubmed/32350331 http://dx.doi.org/10.1038/s41598-020-64129-7

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