FOLFOX Chemotherapy Ameliorates CD8 T Lymphocyte Exhaustion and Enhances Checkpoint Blockade Efficacy in Colorectal Cancer

Background: Colorectal cancer (CRC) is the third most common malignancy worldwide. The presence of CD8 tumor-infiltrating T lymphocytes (TILs) is associated with improved prognosis and therapeutic response in CRC patients. FOLFOX chemotherapy is a standard first-line treatment for patients with CRC....

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Detalles Bibliográficos
Autores principales: Guan, Yue, Kraus, Sean G., Quaney, Michael J., Daniels, Mark A., Mitchem, Jonathan B., Teixeiro, Emma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190812/
https://www.ncbi.nlm.nih.gov/pubmed/32391270
http://dx.doi.org/10.3389/fonc.2020.00586

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190812/
https://www.ncbi.nlm.nih.gov/pubmed/32391270
http://dx.doi.org/10.3389/fonc.2020.00586

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