Cargando…

Performance of metabonomic serum analysis for diagnostics in paediatric tuberculosis

We applied a metabonomic strategy to identify host biomarkers in serum to diagnose paediatric tuberculosis (TB) disease. 112 symptomatic children with presumptive TB were recruited in The Gambia and classified as bacteriologically-confirmed TB, clinically diagnosed TB, or other diseases. Sera were a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Andreas, Nicholas J., Basu Roy, Robindra, Gomez-Romero, Maria, Horneffer-van der Sluis, Verena, Lewis, Matthew R., Camuzeaux, Stephane S. M., Jiménez, Beatriz, Posma, Joram M., Tientcheu, Leopold, Egere, Uzochukwu, Sillah, Abdou, Togun, Toyin, Holmes, Elaine, Kampmann, Beate
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190829/ https://www.ncbi.nlm.nih.gov/pubmed/32350385 http://dx.doi.org/10.1038/s41598-020-64413-6

Ejemplares similares

A three-marker protein biosignature distinguishes tuberculosis from other respiratory diseases in Gambian children
por: Togun, Toyin, et al.
Publicado: (2020)

Protection against mycobacterial infection: A case-control study of mycobacterial immune responses in pairs of Gambian children with discordant infection status despite matched TB exposure
por: Basu Roy, Robindra, et al.
Publicado: (2020)

Vitamin D in Gambian children with discordant tuberculosis (TB) infection status despite matched TB exposure: a case control study
por: Stockdale, Lisa, et al.
Publicado: (2021)

The need to prioritise childhood tuberculosis case detection
por: Nkereuwem, Esin, et al.
Publicado: (2021)

Exploring the perspectives of members of international tuberculosis control and research networks on the impact of COVID-19 on tuberculosis services: a cross sectional survey
por: Nkereuwem, Oluwatosin, et al.
Publicado: (2021)

Anticipating the impact of the COVID-19 pandemic on TB patients and TB control programmes
por: Togun, Toyin, et al.
Publicado: (2020)

Reduced lung function and health-related quality of life after treatment for pulmonary tuberculosis in Gambian children: a cross-sectional comparative study
por: Nkereuwem, Esin, et al.
Publicado: (2023)

Biomarkers for diagnosis of childhood tuberculosis: A systematic review
por: Togun, Toyin Omotayo, et al.
Publicado: (2018)

Elevated serum 25-hydroxy (OH) vitamin D levels are associated with risk of TB progression in Gambian adults
por: Owolabi, Olumuyiwa, et al.
Publicado: (2016)

An Auto-luminescent Fluorescent BCG Whole Blood Assay to Enable Evaluation of Paediatric Mycobacterial Responses Using Minimal Blood Volumes
por: Basu Roy, Robindra, et al.
Publicado: (2019)

Childhood tuberculosis in high burden settings
por: Togun, Toyin
Publicado: (2021)

Childhood TB sequel: evaluating respiratory function after treatment for pulmonary tuberculosis in a prospective cohort of Gambian children – a study protocol
por: Nkereuwem, Esin, et al.
Publicado: (2023)

Diagnosis of paediatric TB using Xpert(®) MTB/RIF Ultra on fresh respiratory samples
por: Sabi, I., et al.
Publicado: (2022)

Immunological consequences of strain variation within the Mycobacterium tuberculosis complex
por: Tientcheu, Leopold D., et al.
Publicado: (2017)

Effect on nasopharyngeal pneumococcal carriage of replacing PCV7 with PCV13 in the Expanded Programme of Immunization in The Gambia
por: Roca, Anna, et al.
Publicado: (2015)

MetaboNetworks, an interactive Matlab-based toolbox for creating, customizing and exploring sub-networks from KEGG
por: Posma, Joram M., et al.
Publicado: (2014)

Metabonomic Investigation of Single and Multiple Strain Trypanosoma brucei brucei Infections
por: Li, Jia V., et al.
Publicado: (2011)

Delay in the diagnosis of pulmonary tuberculosis in The Gambia, West Africa: A cross-sectional study
por: Owolabi, Olumuyiwa A., et al.
Publicado: (2020)

Ethnicity Associated Microbial and Metabonomic Profiling in Newly Diagnosed Ulcerative Colitis
por: Misra, Ravi, et al.
Publicado: (2022)

Metabonomics in toxicity assessment /
Publicado: (2005)

Clinical and Epidemiological Metabonomics
por: Ala-Korpela, Mika, et al.
Publicado: (2011)

Metabonomics and intensive care
por: Antcliffe, David, et al.
Publicado: (2016)

Metabonomics in Gastroenterology and Hepatology
por: Bjerrum, Jacob Tveiten, et al.
Publicado: (2019)

Proteomic and metabonomic biomarkers for hepatocellular carcinoma: a comprehensive review
por: Kimhofer, T, et al.
Publicado: (2015)

Mortality and loss to programme before antiretroviral therapy among HIV-infected children eligible for treatment in The Gambia, West Africa
por: Okomo, Uduak, et al.
Publicado: (2012)

Comparative metabonomic analysis of hepatotoxicity induced by acetaminophen and its less toxic meta-isomer
por: Kyriakides, Michael, et al.
Publicado: (2016)

Metabonomics: Mining for Metabolites in Biofluids
Publicado: (2002)

Metabonomics window into plateau hypoxia
por: Chang, Yue, et al.
Publicado: (2019)

Why the Convention on the Rights of the Child must become a guiding framework for the realization of the rights of children affected by tuberculosis
por: Basu Roy, Robindra, et al.
Publicado: (2016)

Metabonomics-based omics study and atherosclerosis
por: Wu, Duo-jiao, et al.
Publicado: (2011)

Metabonomics Research Progress on Liver Diseases
por: Yu, Mengqian, et al.
Publicado: (2017)

Metabonomic analysis of cerebrospinal fluid in epilepsy
por: Niu, Di, et al.
Publicado: (2022)

Antitumor effect and metabonomics of niclosamide micelles
por: Hang, Jiarong, et al.
Publicado: (2022)

Differential transcriptomic and metabolic profiles of M. africanum- and M. tuberculosis-infected patients after, but not before drug treatment
por: Tientcheu, Leopold D., et al.
Publicado: (2015)

Pre-treatment mortality and loss-to-follow-up in HIV-1, HIV-2 and HIV-1/HIV-2 dually infected patients eligible for antiretroviral therapy in The Gambia, West Africa
por: Togun, Toyin, et al.
Publicado: (2011)

Treatment outcomes among HIV-1 and HIV-2 infected children initiating antiretroviral therapy in a concentrated low prevalence setting in West Africa
por: Okomo, Uduak, et al.
Publicado: (2012)

C-reactive protein, Neopterin and Beta(2) microglobulin levels pre and post TB treatment in The Gambia
por: Mendy, Joseph, et al.
Publicado: (2016)

The Applications and Obstacles of Metabonomics in Traditional Chinese Medicine
por: Liu, Ping, et al.
Publicado: (2012)

Monitoring Healthy Metabolic Trajectories with Nutritional Metabonomics
por: Collino, Sebastiano, et al.
Publicado: (2009)

Progress in Metabonomics of Type 2 Diabetes Mellitus
por: Ma, Quantao, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_3oipemb6v3qv76pg4k7b9qiaef