LSD1-mediated enhancer silencing attenuates retinoic acid signalling during pancreatic endocrine cell development

Developmental progression depends on temporally defined changes in gene expression mediated by transient exposure of lineage intermediates to signals in the progenitor niche. To determine whether cell-intrinsic epigenetic mechanisms contribute to signal-induced transcriptional responses, here we man...

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Detalles Bibliográficos
Autores principales: Vinckier, Nicholas K., Patel, Nisha A., Geusz, Ryan J., Wang, Allen, Wang, Jinzhao, Matta, Ileana, Harrington, Austin R., Wortham, Matthew, Wetton, Nichole, Wang, Jianxun, Jhala, Ulupi S., Rosenfeld, Michael G., Benner, Christopher W., Shih, Hung-Ping, Sander, Maike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190832/
https://www.ncbi.nlm.nih.gov/pubmed/32350257
http://dx.doi.org/10.1038/s41467-020-16017-x

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