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Paper-Based Electrochemical Devices for the Pharmaceutical Field: State of the Art and Perspectives

The current international pharmaceutical scenario encompasses several steps in drug production, with complex and extremely long procedures. In the last few decades, scientific research has been trying to offer valid and reliable solutions to replace or support conventional techniques, in order to fa...

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Autores principales: Antonacci, Amina, Scognamiglio, Viviana, Mazzaracchio, Vincenzo, Caratelli, Veronica, Fiore, Luca, Moscone, Danila, Arduini, Fabiana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190989/
https://www.ncbi.nlm.nih.gov/pubmed/32391344
http://dx.doi.org/10.3389/fbioe.2020.00339
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author Antonacci, Amina
Scognamiglio, Viviana
Mazzaracchio, Vincenzo
Caratelli, Veronica
Fiore, Luca
Moscone, Danila
Arduini, Fabiana
author_facet Antonacci, Amina
Scognamiglio, Viviana
Mazzaracchio, Vincenzo
Caratelli, Veronica
Fiore, Luca
Moscone, Danila
Arduini, Fabiana
author_sort Antonacci, Amina
collection PubMed
description The current international pharmaceutical scenario encompasses several steps in drug production, with complex and extremely long procedures. In the last few decades, scientific research has been trying to offer valid and reliable solutions to replace or support conventional techniques, in order to facilitate drug development procedures. These innovative approaches may have extremely positive effects in the production chain, supplying fast, and cost-effective quality as well as safety tests on active pharmaceutical ingredients (APIs) and their excipients. In this context, the exploitation of electrochemical paper-based analytical devices (ePADs) is still in its infancy, but is particularly promising in the detection of APIs and excipients in tablets, capsules, suppositories, and injections, as well as for pharmacokinetic bioanalysis in real samples.
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spelling pubmed-71909892020-05-08 Paper-Based Electrochemical Devices for the Pharmaceutical Field: State of the Art and Perspectives Antonacci, Amina Scognamiglio, Viviana Mazzaracchio, Vincenzo Caratelli, Veronica Fiore, Luca Moscone, Danila Arduini, Fabiana Front Bioeng Biotechnol Bioengineering and Biotechnology The current international pharmaceutical scenario encompasses several steps in drug production, with complex and extremely long procedures. In the last few decades, scientific research has been trying to offer valid and reliable solutions to replace or support conventional techniques, in order to facilitate drug development procedures. These innovative approaches may have extremely positive effects in the production chain, supplying fast, and cost-effective quality as well as safety tests on active pharmaceutical ingredients (APIs) and their excipients. In this context, the exploitation of electrochemical paper-based analytical devices (ePADs) is still in its infancy, but is particularly promising in the detection of APIs and excipients in tablets, capsules, suppositories, and injections, as well as for pharmacokinetic bioanalysis in real samples. Frontiers Media S.A. 2020-04-23 /pmc/articles/PMC7190989/ /pubmed/32391344 http://dx.doi.org/10.3389/fbioe.2020.00339 Text en Copyright © 2020 Antonacci, Scognamiglio, Mazzaracchio, Caratelli, Fiore, Moscone and Arduini. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Bioengineering and Biotechnology
Antonacci, Amina
Scognamiglio, Viviana
Mazzaracchio, Vincenzo
Caratelli, Veronica
Fiore, Luca
Moscone, Danila
Arduini, Fabiana
Paper-Based Electrochemical Devices for the Pharmaceutical Field: State of the Art and Perspectives
title Paper-Based Electrochemical Devices for the Pharmaceutical Field: State of the Art and Perspectives
title_full Paper-Based Electrochemical Devices for the Pharmaceutical Field: State of the Art and Perspectives
title_fullStr Paper-Based Electrochemical Devices for the Pharmaceutical Field: State of the Art and Perspectives
title_full_unstemmed Paper-Based Electrochemical Devices for the Pharmaceutical Field: State of the Art and Perspectives
title_short Paper-Based Electrochemical Devices for the Pharmaceutical Field: State of the Art and Perspectives
title_sort paper-based electrochemical devices for the pharmaceutical field: state of the art and perspectives
topic Bioengineering and Biotechnology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190989/
https://www.ncbi.nlm.nih.gov/pubmed/32391344
http://dx.doi.org/10.3389/fbioe.2020.00339
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