Cargando…

Intracellular matrix Gla protein promotes tumor progression by activating JAK2/STAT5 signaling in gastric cancer

Matrix Gla protein (MGP) has been widely reported as an extracellular matrix protein with abnormal expression in various types of cancer. However, the function of intracellular MGP in gastric cancer (GC) cells remains largely unknown. Here, we demonstrated aberrantly high expression of intracellular...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Mizhu, Chen, Lei, Chen, Yu, Wei, Rui, Guo, Qingdong, Zhu, Shengquan, Guo, Shuilong, Zhu, Shengtao, Zhang, Shutian, Min, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191194/ https://www.ncbi.nlm.nih.gov/pubmed/32086862 http://dx.doi.org/10.1002/1878-0261.12652

Ejemplares similares

MGP Promotes Colon Cancer Proliferation by Activating the NF-κB Pathway through Upregulation of the Calcium Signaling Pathway
por: Li, Xueqing, et al.
Publicado: (2020)

Downregulation of NONO induces apoptosis, suppressing growth and invasion in esophageal squamous cell carcinoma
por: Cheng, Rui, et al.
Publicado: (2018)

Integrated Analysis Identifies Molecular Signatures and Specific Prognostic Factors for Different Gastric Cancer Subtypes()
por: Min, Li, et al.
Publicado: (2016)

FAM175B promotes apoptosis by inhibiting ATF4 ubiquitination in esophageal squamous cell carcinoma
por: Zhao, Yu, et al.
Publicado: (2019)

miR-92a-3p promotes the proliferation, migration and invasion of esophageal squamous cell cancer by regulating PTEN
por: Li, Xin, et al.
Publicado: (2019)

ECT2 Increases the stability of EGFR and Tumorigenicity by Inhibiting Grb2 Ubiquitination in Pancreatic Cancer
por: Wang, Junxiong, et al.
Publicado: (2021)

M2 Macrophage Derived Extracellular Vesicle-Mediated Transfer of MiR-186-5p Promotes Colon Cancer Progression by Targeting DLC1
por: Guo, Junfeng, et al.
Publicado: (2022)

Liquid Biopsy of Extracellular Vesicle-Derived miR-193a-5p in Colorectal Cancer and Discovery of Its Tumor-Suppressor Functions
por: Wei, Rui, et al.
Publicado: (2020)

Gene regulatory network construction identified NFYA as a diffuse subtype-specific prognostic factor in gastric cancer
por: Cao, Bin, et al.
Publicado: (2018)

Evolution of Matrix Gla and Bone Gla Protein Genes in Jawed Vertebrates
por: Leurs, Nicolas, et al.
Publicado: (2021)

Predict Colon Cancer by Pairing Plasma miRNAs: Establishment of a Normalizer-Free, Cross-Platform Model
por: Qin, Da, et al.
Publicado: (2021)

Matrix Gla protein in tumoral pathology
por: GHEORGHE, SIMONA ROXANA, et al.
Publicado: (2016)

Detection of Pancreatic Ductal Adenocarcinoma by A qPCR-based Normalizer-free Circulating Extracellular Vesicles RNA Signature
por: Qin, Da, et al.
Publicado: (2021)

Association of matrix Gla protein polymorphism and knee osteoarthritis in a chinese population
por: Hui, Wenpeng, et al.
Publicado: (2019)

Cytoplasmic Asporin promotes cell migration by regulating TGF-β/Smad2/3 pathway and indicates a poor prognosis in colorectal cancer
por: Li, Hengcun, et al.
Publicado: (2019)

The potential roles of JAK/STAT signaling in the progression of osteoarthritis
por: Zhou, Qingluo, et al.
Publicado: (2022)

miR193b Promotes Apoptosis of Gastric Cancer Cells via Directly Mediating the Akt Pathway
por: Tian, Ruyue, et al.
Publicado: (2020)

Fetuin, Matrix-Gla Protein and Osteopontin in Calcification of Renal Allografts
por: Lorenzen, Johan M., et al.
Publicado: (2012)

Vitamin D3 Inhibits Helicobacter pylori Infection by Activating the VitD3/VDR-CAMP Pathway in Mice
por: Zhou, Anni, et al.
Publicado: (2020)

Ponicidin Induces Apoptosis via JAK2 and STAT3 Signaling Pathways in Gastric Carcinoma
por: Liu, Yuan-Fei, et al.
Publicado: (2015)

TRIM66 promotes malignant progression of prostate carcinoma through the JAK/STAT pathway
por: Cao, Hongwen, et al.
Publicado: (2020)

Lyssavirus matrix protein cooperates with phosphoprotein to modulate the Jak-Stat pathway
por: Sonthonnax, Florian, et al.
Publicado: (2019)

Cyclin-Dependent Kinase Inhibitor 3 Promoted Cell Proliferation by Driving Cell Cycle from G1 to S Phase in Esophageal Squamous Cell Carcinoma
por: Liu, Juan, et al.
Publicado: (2019)

Gastrokine 2 Regulates the Antitumor Effect of JAK2/STAT3 Pathway in Gastric Cancer
por: Zhou, Yu, et al.
Publicado: (2021)

HOXA10 deteriorates gastric cancer through activating JAK1/STAT3 signaling pathway
por: Chen, Wenchao, et al.
Publicado: (2019)

The Role of Matrix Gla Protein in Ossification and Recovery of the Avian Growth Plate
por: Dan, Harel, et al.
Publicado: (2012)

Is Matrix Gla Protein Associated with Vascular Calcification? A Systematic Review
por: Barrett, Hilary, et al.
Publicado: (2018)

Inactive matrix Gla protein is elevated in patients with inflammatory bowel disease
por: Brnic, Darko, et al.
Publicado: (2020)

Matrix Gla protein regulates adipogenesis and is serum marker of visceral adiposity
por: Li, Chaomin, et al.
Publicado: (2020)

Matrix Gla Protein drives stemness and tumor initiation in ovarian cancer
por: Nieddu, V., et al.
Publicado: (2023)

JAKs and STATs in chemoresistance
por: Costa-Pereira, Ana P
Publicado: (2010)

JAK-STAT and feeding
por: Ladyman, Sharon R., et al.
Publicado: (2013)

RAR-Related Orphan Receptor: An Accelerated Preeclampsia Progression by Activating the JAK/STAT3 Pathway
por: Yu, Ying, et al.
Publicado: (2022)

HLX affects cell cycle and proliferation in AML cells via the JAK/STAT signaling pathway
por: Zhu, Xia-Yin, et al.
Publicado: (2020)

Transcriptome and methylome profiling in a rat model of irritable bowel syndrome induced by stress
por: Zhu, Shengtao, et al.
Publicado: (2018)

Central Hemodynamics in Relation to Circulating Desphospho‐Uncarboxylated Matrix Gla Protein: A Population Study
por: Wei, Fang‐Fei, et al.
Publicado: (2019)

Digesting the Role of JAK-STAT and Cytokine Signaling in Oral and Gastric Cancers
por: Ni, Yanhong, et al.
Publicado: (2022)

Oxymatrine exhibits anti-tumor activity in gastric cancer through inhibition of IL-21R-mediated JAK2/STAT3 pathway
por: Huang, Yanxia, et al.
Publicado: (2018)

Jak2-Independent Activation of Stat3 by Intracellular Angiotensin II in Human Mesangial Cells
por: Singh, Rekha
Publicado: (2011)

Association analyses of the JAK/STAT signaling pathway with the progression and prognosis of colon cancer
por: Tang, Shengbo, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_95iu9kssol2qimtg6917an22ds