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Data on the characterization of a platelet lysate and of the system in which it is included (nanoparticles/hydrogel), intended for the treatment of wounds
Platelet lysate has attracted attention for different biomedical applications, including biological processes where cellular proliferation and migration have been altered. Spectroscopic properties of a platelet lysate obtained from human platelets were performed in order to be incorporated in polyme...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191210/ https://www.ncbi.nlm.nih.gov/pubmed/32373684 http://dx.doi.org/10.1016/j.dib.2020.105529 |
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author | Bernal, Sergio Alcalá, Sergio Cerecedo, Doris Ganem-Rondero, Adriana |
author_facet | Bernal, Sergio Alcalá, Sergio Cerecedo, Doris Ganem-Rondero, Adriana |
author_sort | Bernal, Sergio |
collection | PubMed |
description | Platelet lysate has attracted attention for different biomedical applications, including biological processes where cellular proliferation and migration have been altered. Spectroscopic properties of a platelet lysate obtained from human platelets were performed in order to be incorporated in polymeric nanoparticles and then into a Pluronic(Ⓡ) F127 hydrogel, intended for wound healing (more details can be found at https://doi.org/10.1016/j.ejps.2020.105231 [1]). The platelet lysate (PL) was assessed by ultraviolet, infrared and circular dichroism spectroscopy. The developed hydrogel was also analyzed by infrared spectroscopy to evaluate if the Pluronic(Ⓡ) F127 structure was maintained when the nanoparticles or platelet lysate-loaded nanoparticles were included. The sol-gel transition temperature of the hydrogel was determined through its thermal behavior and by dynamic light scattering. |
format | Online Article Text |
id | pubmed-7191210 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-71912102020-05-05 Data on the characterization of a platelet lysate and of the system in which it is included (nanoparticles/hydrogel), intended for the treatment of wounds Bernal, Sergio Alcalá, Sergio Cerecedo, Doris Ganem-Rondero, Adriana Data Brief Pharmacology, Toxicology and Pharmaceutical Science Platelet lysate has attracted attention for different biomedical applications, including biological processes where cellular proliferation and migration have been altered. Spectroscopic properties of a platelet lysate obtained from human platelets were performed in order to be incorporated in polymeric nanoparticles and then into a Pluronic(Ⓡ) F127 hydrogel, intended for wound healing (more details can be found at https://doi.org/10.1016/j.ejps.2020.105231 [1]). The platelet lysate (PL) was assessed by ultraviolet, infrared and circular dichroism spectroscopy. The developed hydrogel was also analyzed by infrared spectroscopy to evaluate if the Pluronic(Ⓡ) F127 structure was maintained when the nanoparticles or platelet lysate-loaded nanoparticles were included. The sol-gel transition temperature of the hydrogel was determined through its thermal behavior and by dynamic light scattering. Elsevier 2020-04-11 /pmc/articles/PMC7191210/ /pubmed/32373684 http://dx.doi.org/10.1016/j.dib.2020.105529 Text en © 2020 Published by Elsevier Inc. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Pharmacology, Toxicology and Pharmaceutical Science Bernal, Sergio Alcalá, Sergio Cerecedo, Doris Ganem-Rondero, Adriana Data on the characterization of a platelet lysate and of the system in which it is included (nanoparticles/hydrogel), intended for the treatment of wounds |
title | Data on the characterization of a platelet lysate and of the system in which it is included (nanoparticles/hydrogel), intended for the treatment of wounds |
title_full | Data on the characterization of a platelet lysate and of the system in which it is included (nanoparticles/hydrogel), intended for the treatment of wounds |
title_fullStr | Data on the characterization of a platelet lysate and of the system in which it is included (nanoparticles/hydrogel), intended for the treatment of wounds |
title_full_unstemmed | Data on the characterization of a platelet lysate and of the system in which it is included (nanoparticles/hydrogel), intended for the treatment of wounds |
title_short | Data on the characterization of a platelet lysate and of the system in which it is included (nanoparticles/hydrogel), intended for the treatment of wounds |
title_sort | data on the characterization of a platelet lysate and of the system in which it is included (nanoparticles/hydrogel), intended for the treatment of wounds |
topic | Pharmacology, Toxicology and Pharmaceutical Science |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191210/ https://www.ncbi.nlm.nih.gov/pubmed/32373684 http://dx.doi.org/10.1016/j.dib.2020.105529 |
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