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Kynurenine 3-monooxygenase upregulates pluripotent genes through β-catenin and promotes triple-negative breast cancer progression

BACKGROUND: Triple-negative breast cancer (TNBC) is aggressive and has a poor prognosis. Kynurenine 3-monooxygenase (KMO), a crucial kynurenine metabolic enzyme, is involved in inflammation, immune response and tumorigenesis. We aimed to study the role of KMO in TNBC. METHODS: KMO alteration and exp...

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Detalles Bibliográficos
Autores principales:	Huang, Tzu-Ting, Tseng, Ling-Ming, Chen, Ji-Lin, Chu, Pei-Yi, Lee, Chia-Han, Huang, Chun-Teng, Wang, Wan-Lun, Lau, Ka-Yi, Tseng, Mei-Fang, Chang, Yuan-Ya, Chiang, Tzu-Yi, Ueng, Yune-Fang, Lee, Hsin-Chen, Dai, Ming-Shen, Liu, Chun-Yu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Research paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191260/ https://www.ncbi.nlm.nih.gov/pubmed/32268268 http://dx.doi.org/10.1016/j.ebiom.2020.102717

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