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Measurement of absorption and reduced scattering coefficients in Asian human epidermis, dermis, and subcutaneous fat tissues in the 400- to 1100-nm wavelength range for optical penetration depth and energy deposition analysis

Significance: In laser therapy and diagnosis of skin diseases, the irradiated light distribution, which is determined by the absorption coefficient [Formula: see text] and reduced scattering coefficient [Formula: see text] of the epidermis, dermis, and subcutaneous fat, affects the treatment outcome...

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Autores principales: Shimojo, Yu, Nishimura, Takahiro, Hazama, Hisanao, Ozawa, Toshiyuki, Awazu, Kunio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society of Photo-Optical Instrumentation Engineers 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191311/
https://www.ncbi.nlm.nih.gov/pubmed/32356424
http://dx.doi.org/10.1117/1.JBO.25.4.045002
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author Shimojo, Yu
Nishimura, Takahiro
Hazama, Hisanao
Ozawa, Toshiyuki
Awazu, Kunio
author_facet Shimojo, Yu
Nishimura, Takahiro
Hazama, Hisanao
Ozawa, Toshiyuki
Awazu, Kunio
author_sort Shimojo, Yu
collection PubMed
description Significance: In laser therapy and diagnosis of skin diseases, the irradiated light distribution, which is determined by the absorption coefficient [Formula: see text] and reduced scattering coefficient [Formula: see text] of the epidermis, dermis, and subcutaneous fat, affects the treatment outcome and diagnosis accuracy. Although values for [Formula: see text] and [Formula: see text] have been reported, detailed analysis for Asian skin tissues is still lacking. Aim: We present [Formula: see text] and [Formula: see text] measurements of Asian skin tissues in the 400- to 1100-nm wavelength range for evaluating optical penetration depth and energy deposition. Approach: The measurements with Asian human skin samples are performed employing a double integrating sphere spectrometric system and an inverse Monte Carlo technique. Using the measured parameters, the optical penetration depth and energy deposition are quantitatively analyzed. Results: The [Formula: see text] of the epidermis layer varies among different ethnic groups, while the [Formula: see text] of the other layers and the [Formula: see text] of all of the layers exhibit almost no differences. The analysis reveals that the optical penetration depth and the energy deposition affect the photodynamic therapy treatment depth and the heat production in skin tissue, respectively. Conclusions: The experimentally measured values of [Formula: see text] and [Formula: see text] for Asian skin tissues are presented, and the light behavior in Asian skin tissues is analyzed using a layered tissue model.
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spelling pubmed-71913112020-05-06 Measurement of absorption and reduced scattering coefficients in Asian human epidermis, dermis, and subcutaneous fat tissues in the 400- to 1100-nm wavelength range for optical penetration depth and energy deposition analysis Shimojo, Yu Nishimura, Takahiro Hazama, Hisanao Ozawa, Toshiyuki Awazu, Kunio J Biomed Opt General Significance: In laser therapy and diagnosis of skin diseases, the irradiated light distribution, which is determined by the absorption coefficient [Formula: see text] and reduced scattering coefficient [Formula: see text] of the epidermis, dermis, and subcutaneous fat, affects the treatment outcome and diagnosis accuracy. Although values for [Formula: see text] and [Formula: see text] have been reported, detailed analysis for Asian skin tissues is still lacking. Aim: We present [Formula: see text] and [Formula: see text] measurements of Asian skin tissues in the 400- to 1100-nm wavelength range for evaluating optical penetration depth and energy deposition. Approach: The measurements with Asian human skin samples are performed employing a double integrating sphere spectrometric system and an inverse Monte Carlo technique. Using the measured parameters, the optical penetration depth and energy deposition are quantitatively analyzed. Results: The [Formula: see text] of the epidermis layer varies among different ethnic groups, while the [Formula: see text] of the other layers and the [Formula: see text] of all of the layers exhibit almost no differences. The analysis reveals that the optical penetration depth and the energy deposition affect the photodynamic therapy treatment depth and the heat production in skin tissue, respectively. Conclusions: The experimentally measured values of [Formula: see text] and [Formula: see text] for Asian skin tissues are presented, and the light behavior in Asian skin tissues is analyzed using a layered tissue model. Society of Photo-Optical Instrumentation Engineers 2020-04-30 2020-04 /pmc/articles/PMC7191311/ /pubmed/32356424 http://dx.doi.org/10.1117/1.JBO.25.4.045002 Text en © 2021 The Authors https://creativecommons.org/licenses/by/4.0/ Published by SPIE under a Creative Commons Attribution 4.0 Unported License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI.
spellingShingle General
Shimojo, Yu
Nishimura, Takahiro
Hazama, Hisanao
Ozawa, Toshiyuki
Awazu, Kunio
Measurement of absorption and reduced scattering coefficients in Asian human epidermis, dermis, and subcutaneous fat tissues in the 400- to 1100-nm wavelength range for optical penetration depth and energy deposition analysis
title Measurement of absorption and reduced scattering coefficients in Asian human epidermis, dermis, and subcutaneous fat tissues in the 400- to 1100-nm wavelength range for optical penetration depth and energy deposition analysis
title_full Measurement of absorption and reduced scattering coefficients in Asian human epidermis, dermis, and subcutaneous fat tissues in the 400- to 1100-nm wavelength range for optical penetration depth and energy deposition analysis
title_fullStr Measurement of absorption and reduced scattering coefficients in Asian human epidermis, dermis, and subcutaneous fat tissues in the 400- to 1100-nm wavelength range for optical penetration depth and energy deposition analysis
title_full_unstemmed Measurement of absorption and reduced scattering coefficients in Asian human epidermis, dermis, and subcutaneous fat tissues in the 400- to 1100-nm wavelength range for optical penetration depth and energy deposition analysis
title_short Measurement of absorption and reduced scattering coefficients in Asian human epidermis, dermis, and subcutaneous fat tissues in the 400- to 1100-nm wavelength range for optical penetration depth and energy deposition analysis
title_sort measurement of absorption and reduced scattering coefficients in asian human epidermis, dermis, and subcutaneous fat tissues in the 400- to 1100-nm wavelength range for optical penetration depth and energy deposition analysis
topic General
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191311/
https://www.ncbi.nlm.nih.gov/pubmed/32356424
http://dx.doi.org/10.1117/1.JBO.25.4.045002
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