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Management of Choledochal Cysts at a Tertiary Care Centre: A Nine-Year Experience from India
BACKGROUND: Although choledochal cyst disease is seen predominantly in childhood, it is becomingly increasingly diagnosed in adult patients. METHODS: Data of 36 patients with choledochal cysts managed in our institute between January 2010 and December 2018 were retrospectively analyzed. RESULTS: Med...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191366/ https://www.ncbi.nlm.nih.gov/pubmed/32373713 http://dx.doi.org/10.1155/2020/8017460 |
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author | Honnavara Srinivasan, Pranav Anbalagan, Amudhan Shanmugasundaram, Rajendran Obla Lakshmanamoorthy, Naganathbabu |
author_facet | Honnavara Srinivasan, Pranav Anbalagan, Amudhan Shanmugasundaram, Rajendran Obla Lakshmanamoorthy, Naganathbabu |
author_sort | Honnavara Srinivasan, Pranav |
collection | PubMed |
description | BACKGROUND: Although choledochal cyst disease is seen predominantly in childhood, it is becomingly increasingly diagnosed in adult patients. METHODS: Data of 36 patients with choledochal cysts managed in our institute between January 2010 and December 2018 were retrospectively analyzed. RESULTS: Median age at presentation was 37 years (range: 13–72 years). Female-to-male ratio was 3.5 : 1. All patients were symptomatic, and abdominal pain was the most common symptom. 72.2% had other associated conditions. There was a considerable delay from the onset of symptoms to referral, median duration being 348 days. There were 28 cases of type I (77.8%), 5 cases of type IVA (13.9%), and 3 cases of type IVB (8.3%). Cyst excision with Roux-en-Y hepaticojejunostomy was performed in 29 (80.55%) cases. This procedure was combined with a left lateral sectionectomy, left hepatectomy, and radical cholecystectomy in 1, 2, and 1 cases, respectively. Lilly's technique was used in 2 cases, and cyst excision with hepaticoduodenostomy was performed in 1 case. Early complications were seen in 21 patients (58.3%), and late complications were seen in 5 patients (13.8%). 2 patients were found to have associated malignancies. One patient was detected to have cholangiocarcinoma in the resected liver incidentally, and another patient was diagnosed to have gall bladder cancer intraoperatively. CONCLUSION: Choledochal cysts should be considered in the differential diagnosis of adults presenting with epigastric or right hypochondrium pain or jaundice. A thorough preoperative evaluation is required. Cyst excision with Roux-en-Y hepaticojejunostomy forms the standard treatment in most cases. Long-term follow-up is essential for management of complications and early detection of malignant change. |
format | Online Article Text |
id | pubmed-7191366 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-71913662020-05-05 Management of Choledochal Cysts at a Tertiary Care Centre: A Nine-Year Experience from India Honnavara Srinivasan, Pranav Anbalagan, Amudhan Shanmugasundaram, Rajendran Obla Lakshmanamoorthy, Naganathbabu Surg Res Pract Research Article BACKGROUND: Although choledochal cyst disease is seen predominantly in childhood, it is becomingly increasingly diagnosed in adult patients. METHODS: Data of 36 patients with choledochal cysts managed in our institute between January 2010 and December 2018 were retrospectively analyzed. RESULTS: Median age at presentation was 37 years (range: 13–72 years). Female-to-male ratio was 3.5 : 1. All patients were symptomatic, and abdominal pain was the most common symptom. 72.2% had other associated conditions. There was a considerable delay from the onset of symptoms to referral, median duration being 348 days. There were 28 cases of type I (77.8%), 5 cases of type IVA (13.9%), and 3 cases of type IVB (8.3%). Cyst excision with Roux-en-Y hepaticojejunostomy was performed in 29 (80.55%) cases. This procedure was combined with a left lateral sectionectomy, left hepatectomy, and radical cholecystectomy in 1, 2, and 1 cases, respectively. Lilly's technique was used in 2 cases, and cyst excision with hepaticoduodenostomy was performed in 1 case. Early complications were seen in 21 patients (58.3%), and late complications were seen in 5 patients (13.8%). 2 patients were found to have associated malignancies. One patient was detected to have cholangiocarcinoma in the resected liver incidentally, and another patient was diagnosed to have gall bladder cancer intraoperatively. CONCLUSION: Choledochal cysts should be considered in the differential diagnosis of adults presenting with epigastric or right hypochondrium pain or jaundice. A thorough preoperative evaluation is required. Cyst excision with Roux-en-Y hepaticojejunostomy forms the standard treatment in most cases. Long-term follow-up is essential for management of complications and early detection of malignant change. Hindawi 2020-04-20 /pmc/articles/PMC7191366/ /pubmed/32373713 http://dx.doi.org/10.1155/2020/8017460 Text en Copyright © 2020 Pranav Honnavara Srinivasan et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Honnavara Srinivasan, Pranav Anbalagan, Amudhan Shanmugasundaram, Rajendran Obla Lakshmanamoorthy, Naganathbabu Management of Choledochal Cysts at a Tertiary Care Centre: A Nine-Year Experience from India |
title | Management of Choledochal Cysts at a Tertiary Care Centre: A Nine-Year Experience from India |
title_full | Management of Choledochal Cysts at a Tertiary Care Centre: A Nine-Year Experience from India |
title_fullStr | Management of Choledochal Cysts at a Tertiary Care Centre: A Nine-Year Experience from India |
title_full_unstemmed | Management of Choledochal Cysts at a Tertiary Care Centre: A Nine-Year Experience from India |
title_short | Management of Choledochal Cysts at a Tertiary Care Centre: A Nine-Year Experience from India |
title_sort | management of choledochal cysts at a tertiary care centre: a nine-year experience from india |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191366/ https://www.ncbi.nlm.nih.gov/pubmed/32373713 http://dx.doi.org/10.1155/2020/8017460 |
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