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Assessment of Hematological Parameters in Malaria, among Adult Patients Attending the Bamenda Regional Hospital

Malaria, which is responsible for a substantial amount of deaths in endemic countries, has been shown to have both direct and indirect effects on the hematological parameters. Notwithstanding, some hematological parameters among populations living in malaria endemic regions have not been described c...

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Autores principales: Omarine Nlinwe, Nfor, Nange, Tang Bertilla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191389/
https://www.ncbi.nlm.nih.gov/pubmed/32373360
http://dx.doi.org/10.1155/2020/3814513
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author Omarine Nlinwe, Nfor
Nange, Tang Bertilla
author_facet Omarine Nlinwe, Nfor
Nange, Tang Bertilla
author_sort Omarine Nlinwe, Nfor
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description Malaria, which is responsible for a substantial amount of deaths in endemic countries, has been shown to have both direct and indirect effects on the hematological parameters. Notwithstanding, some hematological parameters among populations living in malaria endemic regions have not been described consistently, as a standard for measuring malaria burden. Based on the above fact, this study was designed to assess some hematological changes and their diagnostic values in malaria infected patients. A total of 160 malaria positive adult patients, together with 81 healthy control adults were recruited for the study. For the malaria positive group, the female to male ratio was 1.38 : 1. Specifically, 74.38%, 10.00%, and 15.62% of those in the malaria positive group had mild, moderate, and severe parasitaemia, respectively. Leukemia, anemia, and thrombocytopenia were found to be significantly associated with malaria and were all estimated to be specific for the diagnosis of malaria. Anemia was, however, estimated to be both sensitive and specific for malaria diagnosis. Therefore, anemia offers the most diagnostic value in the malaria infected patients of this study.
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spelling pubmed-71913892020-05-05 Assessment of Hematological Parameters in Malaria, among Adult Patients Attending the Bamenda Regional Hospital Omarine Nlinwe, Nfor Nange, Tang Bertilla Anemia Research Article Malaria, which is responsible for a substantial amount of deaths in endemic countries, has been shown to have both direct and indirect effects on the hematological parameters. Notwithstanding, some hematological parameters among populations living in malaria endemic regions have not been described consistently, as a standard for measuring malaria burden. Based on the above fact, this study was designed to assess some hematological changes and their diagnostic values in malaria infected patients. A total of 160 malaria positive adult patients, together with 81 healthy control adults were recruited for the study. For the malaria positive group, the female to male ratio was 1.38 : 1. Specifically, 74.38%, 10.00%, and 15.62% of those in the malaria positive group had mild, moderate, and severe parasitaemia, respectively. Leukemia, anemia, and thrombocytopenia were found to be significantly associated with malaria and were all estimated to be specific for the diagnosis of malaria. Anemia was, however, estimated to be both sensitive and specific for malaria diagnosis. Therefore, anemia offers the most diagnostic value in the malaria infected patients of this study. Hindawi 2020-04-21 /pmc/articles/PMC7191389/ /pubmed/32373360 http://dx.doi.org/10.1155/2020/3814513 Text en Copyright © 2020 Nfor Omarine Nlinwe and Tang Bertilla Nange. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Omarine Nlinwe, Nfor
Nange, Tang Bertilla
Assessment of Hematological Parameters in Malaria, among Adult Patients Attending the Bamenda Regional Hospital
title Assessment of Hematological Parameters in Malaria, among Adult Patients Attending the Bamenda Regional Hospital
title_full Assessment of Hematological Parameters in Malaria, among Adult Patients Attending the Bamenda Regional Hospital
title_fullStr Assessment of Hematological Parameters in Malaria, among Adult Patients Attending the Bamenda Regional Hospital
title_full_unstemmed Assessment of Hematological Parameters in Malaria, among Adult Patients Attending the Bamenda Regional Hospital
title_short Assessment of Hematological Parameters in Malaria, among Adult Patients Attending the Bamenda Regional Hospital
title_sort assessment of hematological parameters in malaria, among adult patients attending the bamenda regional hospital
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191389/
https://www.ncbi.nlm.nih.gov/pubmed/32373360
http://dx.doi.org/10.1155/2020/3814513
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