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Exploring the Use of Compound-Induced Transcriptomic Data Generated From Cell Lines to Predict Compound Activity Toward Molecular Targets

Pharmaceutical or phytopharmaceutical molecules rely on the interaction with one or more specific molecular targets to induce their anticipated biological responses. Nonetheless, these compounds are also prone to interact with many other non-intended biological targets, also known as off-targets. Un...

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Detalles Bibliográficos
Autores principales: Baillif, Benoît, Wichard, Joerg, Méndez-Lucio, Oscar, Rouquié, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191531/
https://www.ncbi.nlm.nih.gov/pubmed/32391323
http://dx.doi.org/10.3389/fchem.2020.00296

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