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Exploring the Use of Compound-Induced Transcriptomic Data Generated From Cell Lines to Predict Compound Activity Toward Molecular Targets
Pharmaceutical or phytopharmaceutical molecules rely on the interaction with one or more specific molecular targets to induce their anticipated biological responses. Nonetheless, these compounds are also prone to interact with many other non-intended biological targets, also known as off-targets. Un...
Autores principales: | Baillif, Benoît, Wichard, Joerg, Méndez-Lucio, Oscar, Rouquié, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191531/ https://www.ncbi.nlm.nih.gov/pubmed/32391323 http://dx.doi.org/10.3389/fchem.2020.00296 |
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