Direct Synthesis of the Phenanthroviridone Skeleton Using a Highly Regioselective Nitroquinone Diels–Alder Reaction

[Image: see text] A variety of nucleophiles react efficiently with in situ generated nitroquinones. The reaction with substituted resorcinols led to the direct synthesis of the phenanthroviridinone and lagumycin skeleton via a highly regioselective Diels–Alder reaction.

Detalles Bibliográficos
Autores principales: Yu, Huangchao, Fought, Ellie L., Windus, Theresa L., Kraus, George A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191567/
https://www.ncbi.nlm.nih.gov/pubmed/32363281
http://dx.doi.org/10.1021/acsomega.0c00201
Descripción
Sumario:[Image: see text] A variety of nucleophiles react efficiently with in situ generated nitroquinones. The reaction with substituted resorcinols led to the direct synthesis of the phenanthroviridinone and lagumycin skeleton via a highly regioselective Diels–Alder reaction.

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