Direct Synthesis of the Phenanthroviridone Skeleton Using a Highly Regioselective Nitroquinone Diels–Alder Reaction

[Image: see text] A variety of nucleophiles react efficiently with in situ generated nitroquinones. The reaction with substituted resorcinols led to the direct synthesis of the phenanthroviridinone and lagumycin skeleton via a highly regioselective Diels–Alder reaction.

Detalles Bibliográficos
Autores principales: Yu, Huangchao, Fought, Ellie L., Windus, Theresa L., Kraus, George A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191567/
https://www.ncbi.nlm.nih.gov/pubmed/32363281
http://dx.doi.org/10.1021/acsomega.0c00201
_version_ 1783527875297673216
author Yu, Huangchao
Fought, Ellie L.
Windus, Theresa L.
Kraus, George A.
author_facet Yu, Huangchao
Fought, Ellie L.
Windus, Theresa L.
Kraus, George A.
author_sort Yu, Huangchao
collection PubMed
description [Image: see text] A variety of nucleophiles react efficiently with in situ generated nitroquinones. The reaction with substituted resorcinols led to the direct synthesis of the phenanthroviridinone and lagumycin skeleton via a highly regioselective Diels–Alder reaction.
format Online
Article
Text
id pubmed-7191567
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher American Chemical Society
record_format MEDLINE/PubMed
spelling pubmed-71915672020-05-01 Direct Synthesis of the Phenanthroviridone Skeleton Using a Highly Regioselective Nitroquinone Diels–Alder Reaction Yu, Huangchao Fought, Ellie L. Windus, Theresa L. Kraus, George A. ACS Omega [Image: see text] A variety of nucleophiles react efficiently with in situ generated nitroquinones. The reaction with substituted resorcinols led to the direct synthesis of the phenanthroviridinone and lagumycin skeleton via a highly regioselective Diels–Alder reaction. American Chemical Society 2020-04-17 /pmc/articles/PMC7191567/ /pubmed/32363281 http://dx.doi.org/10.1021/acsomega.0c00201 Text en Copyright © 2020 American Chemical Society This is an open access article published under an ACS AuthorChoice License (http://pubs.acs.org/page/policy/authorchoice_termsofuse.html) , which permits copying and redistribution of the article or any adaptations for non-commercial purposes.
spellingShingle Yu, Huangchao
Fought, Ellie L.
Windus, Theresa L.
Kraus, George A.
Direct Synthesis of the Phenanthroviridone Skeleton Using a Highly Regioselective Nitroquinone Diels–Alder Reaction
title Direct Synthesis of the Phenanthroviridone Skeleton Using a Highly Regioselective Nitroquinone Diels–Alder Reaction
title_full Direct Synthesis of the Phenanthroviridone Skeleton Using a Highly Regioselective Nitroquinone Diels–Alder Reaction
title_fullStr Direct Synthesis of the Phenanthroviridone Skeleton Using a Highly Regioselective Nitroquinone Diels–Alder Reaction
title_full_unstemmed Direct Synthesis of the Phenanthroviridone Skeleton Using a Highly Regioselective Nitroquinone Diels–Alder Reaction
title_short Direct Synthesis of the Phenanthroviridone Skeleton Using a Highly Regioselective Nitroquinone Diels–Alder Reaction
title_sort direct synthesis of the phenanthroviridone skeleton using a highly regioselective nitroquinone diels–alder reaction
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191567/
https://www.ncbi.nlm.nih.gov/pubmed/32363281
http://dx.doi.org/10.1021/acsomega.0c00201
work_keys_str_mv AT yuhuangchao directsynthesisofthephenanthroviridoneskeletonusingahighlyregioselectivenitroquinonedielsalderreaction
AT foughtelliel directsynthesisofthephenanthroviridoneskeletonusingahighlyregioselectivenitroquinonedielsalderreaction
AT windustheresal directsynthesisofthephenanthroviridoneskeletonusingahighlyregioselectivenitroquinonedielsalderreaction
AT krausgeorgea directsynthesisofthephenanthroviridoneskeletonusingahighlyregioselectivenitroquinonedielsalderreaction

Ejemplares similares