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Knockdown of long non-coding RNA HOTAIR reverses cisplatin resistance of ovarian cancer cells through inhibiting miR-138-5p-regulated EZH2 and SIRT1

BACKGROUND: Cisplatin resistance (DDP-resistance) remains one of the major causes of poor prognosis in females with ovarian cancer. Long non-coding RNAs (lncRNAs) have been shown to participate in the regulation of cellular processes, including chemoresistance. The aim of this study was to explore t...

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Detalles Bibliográficos
Autores principales: Zhang, Yun, Ai, Hao, Fan, Xue, Chen, Suxian, Wang, Yadi, Liu, Lili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191713/
https://www.ncbi.nlm.nih.gov/pubmed/32349783
http://dx.doi.org/10.1186/s40659-020-00286-3