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CCR2 is localized in microglia and neurons, as well as infiltrating monocytes, in the lumbar spinal cord of ALS mice
It remains controversial whether circulating monocytes expressing CCR2 infiltrate the central nervous system (CNS) and contribute to pathogenicity of amyotrophic lateral sclerosis (ALS). A previous report used conventional immunohistochemistry to show that CCR2 is exclusively expressed by astrocytes...
Autores principales: | Komiya, Hiroyasu, Takeuchi, Hideyuki, Ogawa, Yuki, Hatooka, Yuki, Takahashi, Keita, Katsumoto, Atsuko, Kubota, Shun, Nakamura, Haruko, Kunii, Misako, Tada, Mikiko, Doi, Hiroshi, Tanaka, Fumiaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191738/ https://www.ncbi.nlm.nih.gov/pubmed/32349774 http://dx.doi.org/10.1186/s13041-020-00607-3 |
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