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Low phosphatase activity of LiaS and strong LiaR-DNA affinity explain the unusual LiaS to LiaR in vivo stoichiometry

BACKGROUND: LiaRS mediates Bacillus subtilis response to cell envelope perturbations. A third protein, LiaF, has an inhibitory role over LiaRS in the absence of stimulus. Together, LiaF and LiaRS form a three-component system characterized by an unusual stoichiometry, a 4:1 ratio between LiaS and Li...

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Detalles Bibliográficos
Autores principales:	Jani, Shailee, Sterzenbach, Karen, Adatrao, Vijaya, Tajbakhsh, Ghazal, Mascher, Thorsten, Golemi-Kotra, Dasantila
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191749/ https://www.ncbi.nlm.nih.gov/pubmed/32349670 http://dx.doi.org/10.1186/s12866-020-01796-6

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