Overexpressed immunoglobulin-like transcript (ILT) 4 in lung adenocarcinoma is correlated with immunosuppressive T cell subset infiltration and poor patient outcomes

BACKGROUND: The poor response to current PD-1/PD-L1 inhibitors in lung cancer patients requires development of novel immunotargets. Immunoglobulin-like transcript (ILT)4 is an immunosuppressive molecule mainly expressed in myeloid innate cells. Recent studies showed that ILT4 was highly expressed in...

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Detalles Bibliográficos
Autores principales: Li, Qing, Li, Juan, Wang, Shuyun, Wang, Jingnan, Chen, Xiaozheng, Zhou, Dongmei, Fang, Yuying, Gao, Aiqin, Sun, Yuping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191800/
https://www.ncbi.nlm.nih.gov/pubmed/32368343
http://dx.doi.org/10.1186/s40364-020-00191-7

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