The Effects of the Transforming Growth Factor-β1 (TGF-β1) Signaling Pathway on Cell Proliferation and Cell Migration are Mediated by Ubiquitin Specific Protease 4 (USP4) in Hypertrophic Scar Tissue and Primary Fibroblast Cultures

BACKGROUND: Hypertrophic scar results from an abnormal repair response to trauma in the skin and involves fibroblasts proliferation with increased collagen deposition. Transforming growth factor-β1 (TGF-β1) and TGF-β receptor type I (TGF-βR1) are involved in tissue repair and are increased by ubiqui...

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Detalles Bibliográficos
Autores principales: Huang, Yong, Wang, Yuting, Wang, Xueming, Lin, Lixin, Wang, Peng, Sun, Junjun, Jiang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2020
Materias:
Clinical Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191961/
https://www.ncbi.nlm.nih.gov/pubmed/32308208
http://dx.doi.org/10.12659/MSM.920736

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