A clioquinol-containing Pluronic(®) F127 polymeric micelle system is effective in the treatment of visceral leishmaniasis in a murine model

A clioquinol (ICHQ)-containing Pluronic(®) F127 polymeric micelle system (ICHQ/Mic) was recently shown to be effective against Leishmania amazonensis infection in a murine model. In the present study, ICHQ/Mic was tested against L. infantum infection. BALB/c mice (n = 12 per group) were infected wit...

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Detalles Bibliográficos
Autores principales: Tavares, Grasiele S.V., Mendonça, Débora V.C., Pereira, Isabela A.G., Oliveira-da-Silva, João A., Ramos, Fernanda F., Lage, Daniela P., Machado, Amanda S., Carvalho, Lívia M., Reis, Thiago A.R., Perin, Luísa, Carvalho, Ana Maria R.S., Ottoni, Flaviano M., Ludolf, Fernanda, Freitas, Camila S., Bandeira, Raquel S., Silva, Alessandra M., Chávez-Fumagalli, Miguel A., Duarte, Mariana C., Menezes-Souza, Daniel, Alves, Ricardo J., Roatt, Bruno M., Coelho, Eduardo A.F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: EDP Sciences 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191975/
https://www.ncbi.nlm.nih.gov/pubmed/32351209
http://dx.doi.org/10.1051/parasite/2020027

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