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Chemistry and Neurotrophic Activities of (–)-Talaumidin and Its Derivatives
(–)-Talaumidin (1), a 2,5-biaryl-3,4-dimethyltetrahydrofuran lignan isolated from Aristolochia arcuata Masters, exhibits significant neurite-outgrowth promotion and neuroprotection in primary cultured rat cortical neurons and in NGF-differentiated PC12 cells. The first enantioselective total synthes...
Autores principales: | Harada, Kenichi, Kubo, Miwa, Fukuyama, Yoshiyasu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192021/ https://www.ncbi.nlm.nih.gov/pubmed/32391327 http://dx.doi.org/10.3389/fchem.2020.00301 |
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