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Chemistry and Neurotrophic Activities of (–)-Talaumidin and Its Derivatives

(–)-Talaumidin (1), a 2,5-biaryl-3,4-dimethyltetrahydrofuran lignan isolated from Aristolochia arcuata Masters, exhibits significant neurite-outgrowth promotion and neuroprotection in primary cultured rat cortical neurons and in NGF-differentiated PC12 cells. The first enantioselective total synthes...

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Detalles Bibliográficos
Autores principales: Harada, Kenichi, Kubo, Miwa, Fukuyama, Yoshiyasu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192021/
https://www.ncbi.nlm.nih.gov/pubmed/32391327
http://dx.doi.org/10.3389/fchem.2020.00301

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