Cargando…
Tissue memory CD4+ T cells expressing IL-7 receptor-alpha (CD127) preferentially support latent HIV-1 infection
The primary reservoir for HIV is within memory CD4+ T cells residing within tissues, yet the features that make some of these cells more susceptible than others to infection by HIV is not well understood. Recent studies demonstrated that CCR5-tropic HIV-1 efficiently enters tissue-derived memory CD4...
Autores principales: | Hsiao, Feng, Frouard, Julie, Gramatica, Andrea, Xie, Guorui, Telwatte, Sushama, Lee, Guinevere Q., Roychoudhury, Pavitra, Schwarzer, Roland, Luo, Xiaoyu, Yukl, Steven A., Lee, Sulggi, Hoh, Rebecca, Deeks, Steven G., Jones, R. Brad, Cavrois, Marielle, Greene, Warner C., Roan, Nadia R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192375/ https://www.ncbi.nlm.nih.gov/pubmed/32353080 http://dx.doi.org/10.1371/journal.ppat.1008450 |
Ejemplares similares
-
Phenotypic analysis of the unstimulated in vivo HIV CD4 T cell reservoir
por: Neidleman, Jason, et al.
Publicado: (2020) -
Characterization of HIV-induced remodeling reveals differences in infection susceptibility of memory CD4(+) T cell subsets in vivo
por: Xie, Guorui, et al.
Publicado: (2021) -
Gut and blood differ in constitutive blocks to HIV transcription, suggesting tissue-specific differences in the mechanisms that govern HIV latency
por: Telwatte, Sushama, et al.
Publicado: (2018) -
Subsets of Tissue CD4 T Cells Display Different Susceptibilities to HIV Infection and Death: Analysis by CyTOF and Single Cell RNA-seq
por: Luo, Xiaoyu, et al.
Publicado: (2022) -
Protracted yet coordinated differentiation of long-lived SARS-CoV-2-specific CD8+ T cells during COVID-19 convalescence
por: Ma, Tongcui, et al.
Publicado: (2021)