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Placental transfer of Letermovir & Maribavir in the ex vivo human cotyledon perfusion model. New perspectives for in utero treatment of congenital cytomegalovirus infection
BACKGROUND: Congenital cytomegalovirus infection can lead to severe sequelae. When fetal infection is confirmed, we hypothesize that fetal treatment could improve the outcome. Maternal oral administration of an effective drug crossing the placenta could allow fetal treatment. Letermovir (LMV) and Ma...
Autores principales: | Faure Bardon, Valentine, Peytavin, Gilles, Lê, Minh Patrick, Guilleminot, Tiffany, Elefant, Elisabeth, Stirnemann, Julien, Leruez-Ville, Marianne, Ville, Yves |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192425/ https://www.ncbi.nlm.nih.gov/pubmed/32353010 http://dx.doi.org/10.1371/journal.pone.0232140 |
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