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Adapting Biased Gene Conversion theory to account for intensive GC-content deterioration in the human genome by novel mutations
We examined seventy million well-characterized human mutations, and their impact on G+C-compositional dynamics, in order to understand the formation and maintenance of major genomic nucleotide sequence patterns. Among novel mutations, those that change a strong (S) base pair G:C/C:G to a weak (W) pa...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192473/ https://www.ncbi.nlm.nih.gov/pubmed/32353016 http://dx.doi.org/10.1371/journal.pone.0232167 |