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Focal adhesion kinase and Src mediate microvascular hyperpermeability caused by fibrinogen- γC- terminal fragments

OBJECTIVES: We previously reported microvascular leakage resulting from fibrinogen-γ chain C-terminal products (γC) occurred via a RhoA-dependent mechanism. The objective of this study was to further elucidate the signaling mechanism by which γC induces endothelial hyperpermeability. Since it is kno...

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Detalles Bibliográficos
Autores principales:	Guo, Xiaohua, Eitnier, Rebecca A., Beard, Richard S., Meegan, Jamie E., Yang, Xiaoyuan, Aponte, Alexandra M., Wang, Fang, Nelson, Peter R., Wu, Mack H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192500/ https://www.ncbi.nlm.nih.gov/pubmed/32352989 http://dx.doi.org/10.1371/journal.pone.0231739

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