The genomic landscape of undifferentiated embryonal sarcoma of the liver is typified by C19MC structural rearrangement and overexpression combined with TP53 mutation or loss

Undifferentiated embryonal sarcoma of the liver (UESL) is a rare and aggressive malignancy. Though the molecular underpinnings of this cancer have been largely unexplored, recurrent chromosomal breakpoints affecting a noncoding region on chr19q13, which includes the chromosome 19 microRNA cluster (C...

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Detalles Bibliográficos
Autores principales: Setty, Bhuvana A., Jinesh, Goodwin G., Arnold, Michael, Pettersson, Fredrik, Cheng, Chia-Ho, Cen, Ling, Yoder, Sean J., Teer, Jamie K., Flores, Elsa R., Reed, Damon R., Brohl, Andrew S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192511/
https://www.ncbi.nlm.nih.gov/pubmed/32310940
http://dx.doi.org/10.1371/journal.pgen.1008642

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