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An H3K9 methylation-dependent protein interaction regulates the non-enzymatic functions of a putative histone demethylase

H3K9 methylation (H3K9me) specifies the establishment and maintenance of transcriptionally silent epigenetic states or heterochromatin. The enzymatic erasure of histone modifications is widely assumed to be the primary mechanism that reverses epigenetic silencing. Here, we reveal an inversion of thi...

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Detalles Bibliográficos
Autores principales: Raiymbek, Gulzhan, An, Sojin, Khurana, Nidhi, Gopinath, Saarang, Larkin, Ajay, Biswas, Saikat, Trievel, Raymond C, Cho, Uhn-soo, Ragunathan, Kaushik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192584/
https://www.ncbi.nlm.nih.gov/pubmed/32195666
http://dx.doi.org/10.7554/eLife.53155

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