The genomic landscape of 8-oxodG reveals enrichment at specific inherently fragile promoters

8-Oxo-7,8-dihydro-2′-deoxyguanosine (8-oxodG) is the most common marker of oxidative stress and its accumulation within the genome has been associated with major human health issues such as cancer, aging, cardiovascular and neurodegenerative diseases. The characterization of the different genomic si...

Descripción completa

Detalles Bibliográficos
Autores principales: Gorini, Francesca, Scala, Giovanni, Di Palo, Giacomo, Dellino, Gaetano Ivan, Cocozza, Sergio, Pelicci, Pier Giuseppe, Lania, Luigi, Majello, Barbara, Amente, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192600/
https://www.ncbi.nlm.nih.gov/pubmed/32198884
http://dx.doi.org/10.1093/nar/gkaa175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192600/
https://www.ncbi.nlm.nih.gov/pubmed/32198884
http://dx.doi.org/10.1093/nar/gkaa175

Ejemplares similares