A transient α-helix in the N-terminal RNA recognition motif of polypyrimidine tract binding protein senses RNA secondary structure

The polypyrimidine tract binding protein (PTB) is a multi-domain protein involved in alternative splicing, mRNA localization, stabilization, polyadenylation and translation initiation from internal ribosome entry sites (IRES). In this latter process, PTB promotes viral translation by interacting ext...

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Detalles Bibliográficos
Autores principales: Maris, Christophe, Jayne, Sandrine, Damberger, Fred F, Beusch, Irene, Dorn, Georg, Ravindranathan, Sapna, Allain, Frédéric H-T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192611/
https://www.ncbi.nlm.nih.gov/pubmed/32170319
http://dx.doi.org/10.1093/nar/gkaa155

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