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Structural basis of UCUU RNA motif recognition by splicing factor RBM20

The vertebrate splicing factor RBM20 (RNA binding motif protein 20) regulates protein isoforms important for heart development and function, with mutations in the gene linked to cardiomyopathy. Previous studies have identified the four nucleotide RNA motif UCUU as a common element in pre-mRNA target...

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Detalles Bibliográficos
Autores principales: Upadhyay, Santosh Kumar, Mackereth, Cameron D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192616/
https://www.ncbi.nlm.nih.gov/pubmed/32187365
http://dx.doi.org/10.1093/nar/gkaa168