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Regulation of the RNA and DNA nuclease activities required for Pyrococcus furiosus Type III-B CRISPR–Cas immunity

Type III CRISPR–Cas prokaryotic immune systems provide anti-viral and anti-plasmid immunity via a dual mechanism of RNA and DNA destruction. Upon target RNA interaction, Type III crRNP effector complexes become activated to cleave both target RNA (via Cas7) and target DNA (via Cas10). Moreover, tran...

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Detalles Bibliográficos
Autores principales:	Foster, Kawanda, Grüschow, Sabine, Bailey, Scott, White, Malcolm F, Terns, Michael P
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192623/ https://www.ncbi.nlm.nih.gov/pubmed/32198888 http://dx.doi.org/10.1093/nar/gkaa176

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