Cargando…
A Snu114–GTP–Prp8 module forms a relay station for efficient splicing in yeast
The single G protein of the spliceosome, Snu114, has been proposed to facilitate splicing as a molecular motor or as a regulatory G protein. However, available structures of spliceosomal complexes show Snu114 in the same GTP-bound state, and presently no Snu114 GTPase-regulatory protein is known. We...
Autores principales: | Jia, Junqiao, Ganichkin, Oleg M, Preußner, Marco, Absmeier, Eva, Alings, Claudia, Loll, Bernhard, Heyd, Florian, Wahl, Markus C |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192624/ https://www.ncbi.nlm.nih.gov/pubmed/32196113 http://dx.doi.org/10.1093/nar/gkaa182 |
Ejemplares similares
-
Mutagenesis of Snu114 domain IV identifies a developmental role in meiotic splicing
por: Gautam, Amit, et al.
Publicado: (2019) -
The U5 snRNA Internal Loop 1 Is a Platform for Brr2, Snu114 and Prp8 Protein Binding During U5 snRNP Assembly
por: Nancollis, Verity, et al.
Publicado: (2013) -
Crystal structure, mutational analysis and RNA-dependent ATPase activity of the yeast DEAD-box pre-mRNA splicing factor Prp28
por: Jacewicz, Agata, et al.
Publicado: (2014) -
The FF domains of yeast U1 snRNP protein Prp40 mediate interactions with Luc7 and Snu71
por: Ester, Claudia, et al.
Publicado: (2008) -
Recruitment of a splicing factor to the nuclear lamina for its inactivation
por: Vester, Karen, et al.
Publicado: (2022)