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A multi-layered structure of the interphase chromocenter revealed by proximity-based biotinylation

During interphase centromeres often coalesce into a small number of chromocenters, which can be visualized as distinct, DAPI dense nuclear domains. Intact chromocenters play a major role in maintaining genome stability as they stabilize the transcriptionally silent state of repetitive DNA while ensu...

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Detalles Bibliográficos
Autores principales:	Kochanova, Natalia Y, Schauer, Tamas, Mathias, Grusha Primal, Lukacs, Andrea, Schmidt, Andreas, Flatley, Andrew, Schepers, Aloys, Thomae, Andreas W, Imhof, Axel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192626/ https://www.ncbi.nlm.nih.gov/pubmed/32182352 http://dx.doi.org/10.1093/nar/gkaa145

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