A modified arginine-depleting enzyme NEI-01 inhibits growth of pancreatic cancer cells

Arginine deprivation cancer therapy targets certain types of malignancies with positive result in many studies and clinical trials. NEI-01 was designed as a novel arginine-depleting enzyme comprising an albumin binding domain capable of binding to human serum albumin to lengthen its half-life. In th...

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Detalles Bibliográficos
Autores principales: Chow, Jeremy P. H., Cai, Yijun, Chow, Daniel T. L., Chung, Steven H. K., Chau, Ka-Chun, Ng, Ka-Ying, Leung, Oscar M., Wong, Raymond M. H., Law, Alan W. L., Leung, Yu-On, Kwok, Sui-Yi, Leung, Yun-chung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192632/
https://www.ncbi.nlm.nih.gov/pubmed/32353864
http://dx.doi.org/10.1371/journal.pone.0231633

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