Cargando…

Effect of dapagliflozin alone and in combination with insulin in a rat model of type 1 diabetes

Dapagliﬂozin is a selective sodium-glucose cotransporter 2 (SGLT2) inhibitor; it reduces glucose reabsorption via the kidney and increases the glucose excretion in urine. This inhibitor functions through a unique insulin-independent mechanism, and is therefore a potential new approach for the treatm...

Descripción completa

Detalles Bibliográficos
Autores principales:	SAYED, Noha, ABDALLA, Osama, KILANY, Omnia, DESSOUKI, Amina, YOSHIDA, Toshinori, SASAKI, Kazuaki, SHIMODA, Minoru
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Japanese Society of Veterinary Science 2020
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192721/ https://www.ncbi.nlm.nih.gov/pubmed/32161237 http://dx.doi.org/10.1292/jvms.19-0450

Ejemplares similares

Effects of dapagliflozin in combination with insulin on cytochrome P450 activities in a diabetes type 1 rat model
por: SAYED, Noha, et al.
Publicado: (2021)

Effect of cyclosporin on distribution of methotrexate into the brain of rats
por: OGUSHI, Naofumi, et al.
Publicado: (2015)

Effects of leucovorin (folinic acid) in the methotrexate-treated rat brain
por: OGUSHI, Naofumi, et al.
Publicado: (2018)

CAN a P-gp modulator assist in the control of methotrexate concentrations in the rat brain? −inhibitory effects of rhodamine 123, a specific substrate for P-gp, on methotrexate excretion from the rat brain and its optimal route of administration
por: OGUSHI, Naofumi, et al.
Publicado: (2016)

Oral pharmacokinetics of the acidic drugs, diclofenac and sulfamonomethoxine in male Shiba goats
por: ELBADAWY, Mohamed, et al.
Publicado: (2014)

Oral absorption profiles of sulfonamides in Shiba goats: a comparison among sulfadimidine, sulfadiazine and sulfanilamide
por: ELBADAWY, Mohamed, et al.
Publicado: (2016)

Rapid absorption of diclofenac and acetaminophen after their oral administration to cattle
por: SAWAGUCHI, Akiyo, et al.
Publicado: (2016)

Biliary excretion and pharmacokinetics of several fluoroquinolones after intravenous injection in rabbits
por: SHIMADA, Sumire, et al.
Publicado: (2023)

Oral pharmacokinetics of acetaminophen to evaluate gastric emptying profiles of Shiba goats
por: ELBADAWY, Mohamed, et al.
Publicado: (2015)

Effectiveness of dapagliflozin as an insulin adjunct in type 1 diabetes: a semi-mechanistic exposure-response model
por: Sokolov, Victor, et al.
Publicado: (2023)

Urinary Bladder Weight and Function in a Rat Model of Mild Hyperglycemia and Its Treatment With Dapagliflozin
por: Yesilyurt, Zeynep Elif, et al.
Publicado: (2019)

Effect of Astragali radix extract on pharmacokinetic behavior of dapagliflozin in healthy and type 2 diabetic rats
por: Du, Wandi, et al.
Publicado: (2023)

Dapagliflozin has No Protective Effect on Experimental Pulmonary Arterial Hypertension and Pulmonary Trunk Banding Rat Models
por: Li, Huayang, et al.
Publicado: (2021)

Oral pharmacokinetics of sulfadiazine and sulfamonomethoxine in female Holstein milking cows
por: TAJIMA, Tsuyoshi, et al.
Publicado: (2023)

Dapagliflozin versus empagliflozin in patients with chronic kidney disease
por: Alnsasra, Hilmi, et al.
Publicado: (2023)

Dapagliflozin protects against nonalcoholic steatohepatitis in db/db mice
por: Qiao, Panshuang, et al.
Publicado: (2022)

Risk of Cardiovascular Events and Medical Cost of Dapagliflozin and Dipeptidyl Peptidase-4 Inhibitors
por: Seong, Jong-Mi, et al.
Publicado: (2021)

Economic Evaluation of Dapagliflozin in the Treatment of Patients With Heart Failure: A Systematic Review
por: Wu, Meiyu, et al.
Publicado: (2022)

Dapagliflozin Mediates Plin5/PPARα Signaling Axis to Attenuate Cardiac Hypertrophy
por: Yu, Jing, et al.
Publicado: (2021)

Dapagliflozin Alleviates Hepatic Steatosis by Restoring Autophagy via the AMPK-mTOR Pathway
por: Li, Liuran, et al.
Publicado: (2021)

Dapagliflozin promotes angiogenesis in hindlimb ischemia mice by inducing M2 macrophage polarization
por: Yang, Heng, et al.
Publicado: (2023)

Cost-Effectiveness of Canagliflozin Versus Dapagliflozin Added to Metformin in Patients With Type 2 Diabetes in China
por: Hou, Xingyun, et al.
Publicado: (2019)

Commentary: Dapagliflozin Mediates Plin5/PPARα Signaling Axis to Attenuate Cardiac Hypertrophy
por: Liu, Zengying, et al.
Publicado: (2022)

Acute and Long-Term Treatment With Dapagliflozin and Association With Serum Soluble Urokinase Plasminogen Activator Receptor
por: Rotbain Curovic, Viktor, et al.
Publicado: (2022)

Dapagliflozin alleviates myocardial ischemia/reperfusion injury by reducing ferroptosis via MAPK signaling inhibition
por: Chen, Weixiang, et al.
Publicado: (2023)

Hepatoprotective Effect of Cranberry Nutraceutical Extract in Non-alcoholic Fatty Liver Model in Rats: Impact on Insulin Resistance and Nrf-2 Expression
por: Faheem, Safaa A., et al.
Publicado: (2020)

Pharmacokinetics and pharmacodynamics of dapagliflozin in combination with insulin in Japanese patients with type 1 diabetes
por: Watada, Hirotaka, et al.
Publicado: (2018)

Possible drug–drug interaction in dogs and cats resulted from alteration in drug metabolism: A mini review
por: Sasaki, Kazuaki, et al.
Publicado: (2015)

High-Salt Attenuates the Efficacy of Dapagliflozin in Tubular Protection by Impairing Fatty Acid Metabolism in Diabetic Kidney Disease
por: Zou, Meina, et al.
Publicado: (2021)

Quantitative effects of sodium–glucose cotransporter-2 inhibitors dapagliflozin and empagliflozin on quality of life in heart failure patients
por: Wang, Dong-Dong, et al.
Publicado: (2022)

Anticancer Effects of Amlodipine Alone or in Combination With Gefitinib in Non-Small Cell Lung Cancer
por: Fu, Bingjie, et al.
Publicado: (2022)

Dapagliflozin Ameliorates Diabetic Kidney Disease via Upregulating Crry and Alleviating Complement Over-activation in db/db Mice
por: Chang, Dong-Yuan, et al.
Publicado: (2021)

Dapagliflozin Alleviates Renal Fibrosis by Inhibiting RIP1-RIP3-MLKL-Mediated Necroinflammation in Unilateral Ureteral Obstruction
por: Xuan, Mei Ying, et al.
Publicado: (2022)

Dapagliflozin Protects Methamphetamine-Induced Cardiomyopathy by Alleviating Mitochondrial Damage and Reducing Cardiac Function Decline in a Mouse Model
por: He, Shanqing, et al.
Publicado: (2022)

Bone Protective Effects of Danggui Buxue Tang Alone and in Combination With Tamoxifen or Raloxifene in vivo and in vitro
por: Zhou, Li-Ping, et al.
Publicado: (2018)

Pharmacotherapy of Traumatic Childhood Aphasia: Beneficial Effects of Donepezil Alone and Combined With Intensive Naming Therapy
por: Dávila, Guadalupe, et al.
Publicado: (2020)

Safety and Efficacy of Therapeutic Cancer Vaccines Alone or in Combination With Immune Checkpoint Inhibitors in Cancer Treatment
por: Zhao, Jing, et al.
Publicado: (2019)

Anlotinib Alone or in Combination With Temozolomide in the Treatment of Recurrent High-Grade Glioma: A Retrospective Analysis
por: Yang, Qunying, et al.
Publicado: (2021)

Comparison of pneumonitis risk between immunotherapy alone and in combination with chemotherapy: an observational, retrospective pharmacovigilance study
por: Li, Huixia, et al.
Publicado: (2023)

A SGLT2 Inhibitor Dapagliflozin Alleviates Diabetic Cardiomyopathy by Suppressing High Glucose-Induced Oxidative Stress in vivo and in vitro
por: Xing, Yu-jie, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_iol52i2fpsm4kbagdm2u191pg7