Inhibition of RIPK3 Pathway Attenuates Intestinal Inflammation and Cell Death of Inflammatory Bowel Disease and Suppresses Necroptosis in Peripheral Mononuclear Cells of Ulcerative Colitis Patients

Receptor-interacting serine/threonine-protein kinase (RIPK) 3 is a member of the TNF receptor-I signaling complex and mediates necroptosis, an inflammatory cell death. Ulcerative colitis (UC) is an excessive inflammatory disease caused by uncontrolled T cell activation. The current study is aimed to...

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Detalles Bibliográficos
Autores principales: Lee, Seung Hoon, Kwon, Ji ye, Moon, Jeonghyeon, Choi, JeongWon, Jhun, Jooyeon, Jung, KyungAh, Cho, Keun-Hyung, Darlami, Om, Lee, Han Hee, Jung, Eun Sun, Shin, Dong Yun, Lee, Bo-In, Cho, Mi-La
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Immunologists 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192830/
https://www.ncbi.nlm.nih.gov/pubmed/32395368
http://dx.doi.org/10.4110/in.2020.20.e16

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