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Neurons promote encephalitogenic CD4(+) lymphocyte infiltration in experimental autoimmune encephalomyelitis

Multiple sclerosis (MS) is an autoimmune disease of the central nervous system characterized by neuroinflammation, leading to demyelination and axonal degeneration. Neuronal excitotoxity mediated by Ca(2+)/calmodulin-dependent protein kinase IIα (CaMKIIα) results in neuronal damage in experimental a...

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Detalles Bibliográficos
Autores principales:	Nakazato, Yuki, Fujita, Yuki, Nakazato, Masamitsu, Yamashita, Toshihide
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192891/ https://www.ncbi.nlm.nih.gov/pubmed/32355314 http://dx.doi.org/10.1038/s41598-020-64363-z

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