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Analysis of TRPA1 antagonist, A-967079, in plasma using high-performance liquid chromatography tandem mass-spectrometry

The noxious effects from exposure to toxic inhalation hazards (TIHs, such as isocyanates, chlorine, etc.) are known to be triggered by the activation of transient receptor potential ankyrin 1 (TRPA1) ion channel. Antagonists of TRPA1 have shown near complete attenuation of the noxious effects from T...

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Detalles Bibliográficos
Autores principales: Gyamfi, Obed A., Bortey-Sam, Nesta, Donkor, Abigail B., White, Carl W., Logue, Brian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192962/
https://www.ncbi.nlm.nih.gov/pubmed/32373387
http://dx.doi.org/10.1016/j.jpha.2019.12.005