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The enigma of gastroesophageal reflux disease among convalescing infants in the NICU: It is time to rethink
Gastroesophageal reflux (GER) can be a normal physiological process, or can be bothersome, when aerodigestive consequences are associated; the latter is often interpreted as GER disease (GERD). However, the distinction between these two entities remains an enigma among infants surviving after neonat...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
King Faisal Specialist Hospital and Research Centre
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193076/ https://www.ncbi.nlm.nih.gov/pubmed/32373699 http://dx.doi.org/10.1016/j.ijpam.2020.03.001 |
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author | Badran, Eman F. Jadcherla, Sudarshan |
author_facet | Badran, Eman F. Jadcherla, Sudarshan |
author_sort | Badran, Eman F. |
collection | PubMed |
description | Gastroesophageal reflux (GER) can be a normal physiological process, or can be bothersome, when aerodigestive consequences are associated; the latter is often interpreted as GER disease (GERD). However, the distinction between these two entities remains an enigma among infants surviving after neonatal intensive care (NICU) care. Symptoms related to GERD are heterogeneous, and are often managed with changes in diet, feeding methods, and acid suppressive therapy. However, none of these approaches have been well-tested in neonates; hence practice variation is very high world-wide. In this paper, we explain the variation in diagnosis, pathophysiology of the clinical presentation, and highlight approaches to diagnosis and management. |
format | Online Article Text |
id | pubmed-7193076 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | King Faisal Specialist Hospital and Research Centre |
record_format | MEDLINE/PubMed |
spelling | pubmed-71930762020-05-05 The enigma of gastroesophageal reflux disease among convalescing infants in the NICU: It is time to rethink Badran, Eman F. Jadcherla, Sudarshan Int J Pediatr Adolesc Med Article Gastroesophageal reflux (GER) can be a normal physiological process, or can be bothersome, when aerodigestive consequences are associated; the latter is often interpreted as GER disease (GERD). However, the distinction between these two entities remains an enigma among infants surviving after neonatal intensive care (NICU) care. Symptoms related to GERD are heterogeneous, and are often managed with changes in diet, feeding methods, and acid suppressive therapy. However, none of these approaches have been well-tested in neonates; hence practice variation is very high world-wide. In this paper, we explain the variation in diagnosis, pathophysiology of the clinical presentation, and highlight approaches to diagnosis and management. King Faisal Specialist Hospital and Research Centre 2020-03 2020-03-05 /pmc/articles/PMC7193076/ /pubmed/32373699 http://dx.doi.org/10.1016/j.ijpam.2020.03.001 Text en © 2020 Publishing services provided by Elsevier B.V. on behalf of King Faisal Specialist Hospital & Research Centre (General Organization), Saudi Arabia. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Article Badran, Eman F. Jadcherla, Sudarshan The enigma of gastroesophageal reflux disease among convalescing infants in the NICU: It is time to rethink |
title | The enigma of gastroesophageal reflux disease among convalescing infants in the NICU: It is time to rethink |
title_full | The enigma of gastroesophageal reflux disease among convalescing infants in the NICU: It is time to rethink |
title_fullStr | The enigma of gastroesophageal reflux disease among convalescing infants in the NICU: It is time to rethink |
title_full_unstemmed | The enigma of gastroesophageal reflux disease among convalescing infants in the NICU: It is time to rethink |
title_short | The enigma of gastroesophageal reflux disease among convalescing infants in the NICU: It is time to rethink |
title_sort | enigma of gastroesophageal reflux disease among convalescing infants in the nicu: it is time to rethink |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193076/ https://www.ncbi.nlm.nih.gov/pubmed/32373699 http://dx.doi.org/10.1016/j.ijpam.2020.03.001 |
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